http://jcps.bjmu.edu.cn

中国药学(英文版) ›› 2020, Vol. 29 ›› Issue (11): 780-792.DOI: 10.5246/jcps.2020.11.071

• 【综 述】 • 上一篇    下一篇

桑叶及其提取物对肠道功能的调节作用

王亚文, 段晓峰, 程晓晓, 张邈鑫, 李丽, 赵丁*   

  1. 河北医科大学 药学院 生药学系, 河北 石家庄 050017
  • 收稿日期:2020-08-20 修回日期:2020-09-15 出版日期:2020-11-30 发布日期:2020-09-20
  • 通讯作者: Tel.: +86-311-86266004; Fax: +86-311-85917887; E-mail: zhaodingd@163.com
  • 作者简介:Ding Zhao, Doctor, Professor, doctoral supervisor, is currently the director of the Department of Pharmacognosy, School of Pharmacy, Hebei Medical University, the person in charge of the Department of Traditional Chinese Medicine, and the person in charge of the Medical Plant Research Center of Hebei Medical University.
  • 基金资助:
    The Key Generic Technology Research Project of High-Quality Agricultural Development of Hebei Province (Grant No. 20327121D); Biomedical Development and Transformation Research Project of Hebei Province (Grant No. 2020TXZH05) and Science and Technology Research Project of Higher Education Institutions of Hebei Province (Grant No. 2019188).

The regulatory effects of mulberry leaf and its extract on intestinal function

Yawen Wang, Xiaofeng Duan, Xiaoxiao Cheng, Miaoxin Zhang, Li Li, Ding Zhao*   

  1. School of Pharmacy, Hebei Medical University, Shijiazhuang Hebei 050017, China
  • Received:2020-08-20 Revised:2020-09-15 Online:2020-11-30 Published:2020-09-20
  • Contact: Tel.: +86-311-86266004; Fax: +86-311-85917887; E-mail: zhaodingd@163.com
  • About author:Ding Zhao, Doctor, Professor, doctoral supervisor, is currently the director of the Department of Pharmacognosy, School of Pharmacy, Hebei Medical University, the person in charge of the Department of Traditional Chinese Medicine, and the person in charge of the Medical Plant Research Center of Hebei Medical University.
  • Supported by:
    The Key Generic Technology Research Project of High-Quality Agricultural Development of Hebei Province (Grant No. 20327121D); Biomedical Development and Transformation Research Project of Hebei Province (Grant No. 2020TXZH05) and Science and Technology Research Project of Higher Education Institutions of Hebei Province (Grant No. 2019188).

摘要:

自古以来桑叶就有显著的肠道调节作用。本文综述了近年来研究桑叶的相关文章, 总结了桑叶成分的生物活性和其对人体肠道调节作用的研究进展及相应的机制。桑叶中的多种成分可以单独或协同影响人体肠道, 通过直接和间接的方式促进小肠消化吸收运输功能、调节菌群平衡以及增强肠道黏膜的屏障作用来提高该部位的免疫力等, 促进肠道疾病的康复。

 

关键词: 桑叶, 桑叶提取物, 肠道功能

Abstract:

Since ancient times, mulberry leaf has a prominent intestinal regulatory effect, and the close relationship between intestinal diseases and other diseases has attracted more and more attention. This article reviewed the relevant articles on the mulberry leaf in recent years and summarized the research progress of mulberry leaf’s biological activities and their effects on human intestinal regulation and the corresponding mechanisms. Multiple components in the mulberry leaf can individually or synergistically affect the human intestine, directly and indirectly promote the digestion, absorption, and transport function of the small intestine, adjust the balance of the flora, enhance the barrier function of the intestinal mucosa, improve the immunity of the part, and facilitate the intestine recovery from illness.

Key words: Mulberry leaf, Mulberry leaf extract, Intestinal function

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