蒿属植物中倍半萜类成分及其生物活性研究进展

doi:10.5246/jcps.2017.05.034

中国药学(英文版) ›› 2017, Vol. 26 ›› Issue (5): 317-334.DOI: 10.5246/jcps.2017.05.034

• 【综述】 • 下一篇

蒿属植物中倍半萜类成分及其生物活性研究进展

张来宾¹, 段金廒², 吕洁丽^1*

1. 新乡医学院药学院, 河南新乡 453003
2. 南京中医药大学江苏省中药资源产业化过程协同创新中心, 江苏南京 210023

收稿日期:2017-03-07 修回日期:2017-04-25 出版日期:2017-05-26 发布日期:2017-05-28
通讯作者: Tel.: +86-0373-3831652, E-mail: jielilv2009@xxmu.edu.cn
基金资助:
National Natural Science Foundation of China (Grant No. 31400305 and 81202916), the Science and Technology Project of Henan Province (Grant No. 152102310113), the Science and Technology Project of the Education Department of Henan Province (Grant No. 14A360012), and the Project for Youth Backbone Teachers in the University of Henan Province (Grant No. 2015GGJS-130).

Phytochemistry and bioactivities of sesquiterpenoids from the Artemisia species

Laibin Zhang¹, Jinao Duan², Jieli Lv^1*

1. School of Pharmacy, Xinxiang Medical University, Xinxiang 453003, China
2. Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, Nanjing 210023, China

Received:2017-03-07 Revised:2017-04-25 Online:2017-05-26 Published:2017-05-28
Contact: Tel.: +86-0373-3831652, E-mail: jielilv2009@xxmu.edu.cn
Supported by:
National Natural Science Foundation of China (Grant No. 31400305 and 81202916), the Science and Technology Project of Henan Province (Grant No. 152102310113), the Science and Technology Project of the Education Department of Henan Province (Grant No. 14A360012), and the Project for Youth Backbone Teachers in the University of Henan Province (Grant No. 2015GGJS-130).

摘要/Abstract

摘要：

蒿属为菊科中种类最多、分布最广的一个属。倍半萜类成分是该属植物中主要的活性成分之一, 具有抗炎、免疫调节、抗肿瘤、抗疟、镇痛、抗菌等广泛的生物活性。本文对2010至2016年7月从蒿属植物中分离得到的倍半萜类成分的结构及生物活性进行了综述, 同时对其开发利用的潜在前景进行了展望。

关键词: 蒿属, 倍半萜, 植物化学, 生物活性

Abstract:

The genus Artemisia is one of the largest and most widely distributed genera of the family Compositae. One type of the mainly active metabolites found in the Artemisia plants is sesquiterpenoids with extensive biological activities, including anti-inflammatory, immunomodulatory, anti-tumour, antimalarial, antinociceptive, antimicrobial and other activities. In this review, wecomprehensively summarized the progressconcerning the phytochemistry and biological activities of sesquiterpenoids obtained from the Artemisiaspecies from 2010 to July 2016. Furthermore,several future research perspectives and development of sesquiterpenoids as potential therapeutic agents were discussed as well.

Key words: Artemisia, Sesquiterpenoids, Phytochemsitry, Bioactivities

中图分类号:

R284

Supporting:

张来宾, 段金廒, 吕洁丽. 蒿属植物中倍半萜类成分及其生物活性研究进展[J]. 中国药学(英文版), 2017, 26(5): 317-334.

Laibin Zhang, Jinao Duan, Jieli Lv. Phytochemistry and bioactivities of sesquiterpenoids from the Artemisia species[J]. Journal of Chinese Pharmaceutical Sciences, 2017, 26(5): 317-334.

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蒿属植物中倍半萜类成分及其生物活性研究进展

Phytochemistry and bioactivities of sesquiterpenoids from the Artemisia species

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