劲直刺桐化学成分研究

doi:10.5246/jcps.2021.12.083

中国药学(英文版) ›› 2021, Vol. 30 ›› Issue (12): 969-975.DOI: 10.5246/jcps.2021.12.083

劲直刺桐化学成分研究

李凤秋, 毕德文, 梁雪松, 罗瑞龙, 庄红丹, 王利勤^*()

云南师范大学化学化工学院, 云南昆明 650500

收稿日期:2021-06-28 修回日期:2021-07-15 接受日期:2021-09-04 出版日期:2021-12-24 发布日期:2021-12-20
通讯作者: 王利勤
作者简介:
+ Tel.: +86-871-5941088, E-mail: lqwang@ynnu.edu.cn
基金资助:
National Natural Science Foundation of China (Grant No. 32060099).

Chemical constituents of the twigs and leaves of Erythrina strica

Fengqiu Li, Dewen Bi, Xuesong Liang, Ruilong Luo, Hongdan Zhuang, Liqin Wang^*()

School of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650500, China

Received:2021-06-28 Revised:2021-07-15 Accepted:2021-09-04 Online:2021-12-24 Published:2021-12-20
Contact: Liqin Wang

摘要/Abstract

摘要：

采用现代多种色谱技术对劲直刺桐Erythrina strica Roxb枝叶的乙酸乙酯萃取物进行化学成分分离纯化, 得到15个化合物, 化合物类型涉及倍半萜、三萜、甾体、木脂素等, 利用波谱技术和文献对照鉴定它们的结构分别为: loliolide (1), phaseic acid (2), pinnatififidanoid A (3), soyasapogenol E (4), 大豆皂醇B (5), 2α,3α,19α,23-tetrahydroxyurs-12-en-28-oic acid (6), 3β,22β,24-trihydroxyolean-12-en-29-oic acid (7), (23Z)-9,19-环阿尔廷-23-烯-3β,25-二醇 (8), 3,4-二羟基苯甲酸 (9), (+)-丁香脂素 (10), (E)-4-hydroxy-dodec-2-enedioic acid (11), lutein (12), 7β-羟基豆甾醇(13), β-谷甾醇(14), 胡萝卜苷 15)。其中倍半萜类成分为首次报道从刺桐Erythrina属植物中得到; 除了化合物13–15外, 其余化合物皆是首次从该植物中分离得到。

关键词: 刺桐Erythrina属, 劲直刺桐, 倍半萜

Abstract:

A total of 15 compounds were extracted from the ethyl acetate extraction of the twigs and leaves of Erythrina strica. Based on NMR spectral data, their structures were identified as loliolide (1), phaseic acid (2), pinnatififidanoid A (3), soyasapogenol E (4), soyasapogenol B (5), 2α,3α,19α,23-tetrahydroxyurs-12-en-28-oic acid (6), 3β,22β,24-trihydroxyolean-12-en-29-oic acid (oxytrogenin) (7), (23Z)-9,19-cycloart-23-ene-3β,25-diol (8), 3,4-dihydroxybenzoic acid (9), syringaresinol (10), (E)-4-hydroxy-dodec-2-enedioic acid (11), lutein (12), ergosterol-5,8-peroxide (13), β-sitosterol (14), and daucosterol (15). Except for compounds 13–15, all the compounds were isolated from this plant for the first time. Moreover, sesquiterpenoids were isolated from Erythrina genus for the first time.

Key words: Erythrina, Erythrina strica, Sesquiterpenoid

Supporting:

李凤秋, 毕德文, 梁雪松, 罗瑞龙, 庄红丹, 王利勤. 劲直刺桐化学成分研究[J]. 中国药学(英文版), 2021, 30(12): 969-975.

Fengqiu Li, Dewen Bi, Xuesong Liang, Ruilong Luo, Hongdan Zhuang, Liqin Wang. Chemical constituents of the twigs and leaves of Erythrina strica[J]. Journal of Chinese Pharmaceutical Sciences, 2021, 30(12): 969-975.

图/表 1

参考文献 18

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劲直刺桐化学成分研究

Chemical constituents of the twigs and leaves of Erythrina strica

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