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• 研究论文 • 上一篇    

苏木的化学成分研究

陈玉平, 刘蕾, 周雨虹, 温晶, 姜勇, 屠鹏飞*

  

  1. 北京大学 中医药现代研究中心, 北京 100083
  • 收稿日期:2007-10-09 修回日期:2008-01-10 出版日期:2008-03-15 发布日期:2008-03-15
  • 通讯作者: 屠鹏飞*

Chemical constituents from Sappan Lignum

Yu-Ping Chen, Lei Liu, Yu-Hong Zhou, Jing Wen, Yong Jiang, Peng-Fei Tu*   

  1. Peking University Modern Research Center for Traditional Chinese Medicines, Beijing 100083, China
  • Received:2007-10-09 Revised:2008-01-10 Online:2008-03-15 Published:2008-03-15
  • Contact: Peng-Fei Tu*

摘要:

研究苏木Caesalpinia sappan L.的化学成分。利用溶剂萃取, 反复硅胶、凝胶柱色谱和反相硅胶等手段进行分离纯化, 根据理化性质、波谱数据进行结构鉴定。分离并鉴定了14个化合物, 分别为巴西苏木素(1), 苏木酮B(2), (E)-3-(3,4-dihydroxybenzylidene)-7-hydroxychroman-4-one (3), 3-去氧苏木酮B(4), brazilide A(5), 1, 7-二羟基口山(6), 槲皮素(7), 鼠李素(8), 苏木查耳酮(9), 3-去氧苏木查耳酮(10), butein(11), 2,4,5-三羟基苯甲醛(12), 3,8,9-trihydroxy-6H-benzo[c]chromen-6-one(13), -谷甾醇(14)。化合物1213为两个新天然产物, 首次报道了化合物13的碳谱数据。化合物6为首次从豆科植物中分离得到, 也是云实属分离得到的第一个口山酮类化合物。

关键词: 苏木, 苏木, 苏木, 化学成分, 化学成分, 化学成分, 化学分类学, 化学分类学, 化学分类学

Abstract:

To study the chemical constituents of Sappan Lignum. Chemical constituents were isolated by method of solvent extraction, repeated chromatography with silica gel, Sephadex LH-20, and ODS. The structures were elucidated based on spectroscopic data. Fourteen compounds were isolated and their structures were identified as brazilin (1), sappanone B (2), (E)-3-(3,4-dihydroxybenzylidene)-7-hydroxychroman-4-one (3), 3-deoxysappanone B (4), brazilide A (5), euxanthone (6), quercetin (7), rhamnetin (8), sappanchalcone (9), 3-deoxysappanchalcone (10), butein (11), 2,4,5-trihydroxybenzaldehyde (12), 3,8,9-trihydroxy-6H-benzo[c]chromen-6-one (13) and β-sitosterol (14). Compounds 12 and 13 were two new natural compounds, and the 13C NMR data of compound 13 were reported for the first time. Compound 6 was the first xanthone isolated from the genus Caesalpinia.

Key words: Caesalpinia sappan, Caesalpinia sappan, Chemical constituents, Chemical constituents, Chemotaxonomy, Chemotaxonomy

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Supporting: *Corresponding author. Tel./fax: 86-10-82802750