临床药师对婴幼儿万古霉素血药浓度监测情况分析

doi:10.5246/jcps.2015.04.035

中国药学(英文版) ›› 2015, Vol. 24 ›› Issue (4): 263-266.DOI: 10.5246/jcps.2015.04.035

临床药师对婴幼儿万古霉素血药浓度监测情况分析

张金莲, 周佳, 陈霁晖, 陈婷, 刘艳, 田怀平, 张健^*

上海交通大学附属新华医院药剂科, 上海 200092

收稿日期:2015-01-02 修回日期:2015-01-18 出版日期:2015-04-28 发布日期:2015-02-12
通讯作者: Tel.: 86-21-25077162
基金资助:
Shanghai Outstanding Young University Teachers Research and Special Funds (Grant No. ZZjdyx13089, Science and Technology Commission of Shanghai Municipality Grants (Grant No. 12DZ1930404).

Analysis for the vancomycin plasma concentration data in infants by clinical pharmacists

Jinlian Zhang, Jia Zhou, Jihui Chen, Ting Chen, Yan Liu, Huaiping Tian, Jian Zhang^*

Department of Pharmacy, Xinhua Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200092, China

Received:2015-01-02 Revised:2015-01-18 Online:2015-04-28 Published:2015-02-12
Contact: Tel.: 86-21-25077162
Supported by:
Shanghai Outstanding Young University Teachers Research and Special Funds (Grant No. ZZjdyx13089, Science and Technology Commission of Shanghai Municipality Grants (Grant No. 12DZ1930404).

摘要/Abstract

摘要：

临床药师对2013–2014年婴幼儿病区使用万古霉素的患儿进行血药浓度监测, 根据监测结果进行调整用药剂量。此文章对监测结果进行分析总结, 讨论万古霉素在新生儿中监测的必要性以及临床药师在此过程中发挥的作用。分析表明,对新生儿常规进行万古霉素血药浓度监测极其必要, 而临床药师对使用万古霉素的患儿进行用药监护, 参与到临床治疗方案调整当中, 可以增加万古霉素使用的有效性及预防不良反应的发生, 是一种新型的治疗模式。

关键词: 临床药师, 万古霉素, 婴幼儿, 治疗药物浓度监测

Abstract:

In the present study, clinical pharmacists monitored the blood concentration of vancomycin in children in the Infant Ward from 2013 to 2014, and the drug dose was adjusted according to its plasma concentration. Moreover, we analyzed the plasma concentration of vancomycin in infants in the hospital from 2013 to 2014. Simultaneously, we also discussed the necessity of regular therapeutic drug monitoring of vancomycin in infants, and the important role of clinical pharmacists was further explored. The results showed that it was necessary to routinely monitor the therapeutic drug in infants. Clinical pharmacists performed medication monitoring, which improved the effectiveness of vancomycin and prevented its adverse effects. In addition, it is a new treatment model for the participation of clinical pharmacists in the clinical treatment.

Key words: Clinical pharmacists, Vancomycin, Infants, Therapeutic drug monitoring

中图分类号:

R969

Supporting:

张金莲, 周佳, 陈霁晖, 陈婷, 刘艳, 田怀平, 张健. 临床药师对婴幼儿万古霉素血药浓度监测情况分析[J]. 中国药学(英文版), 2015, 24(4): 263-266.

Jinlian Zhang, Jia Zhou, Jihui Chen, Ting Chen, Yan Liu, Huaiping Tian, Jian Zhang. Analysis for the vancomycin plasma concentration data in infants by clinical pharmacists[J]. Journal of Chinese Pharmaceutical Sciences, 2015, 24(4): 263-266.

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临床药师对婴幼儿万古霉素血药浓度监测情况分析

Analysis for the vancomycin plasma concentration data in infants by clinical pharmacists

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