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A new ent-pimarane diterpenoid from Siegesbeckia pubescens

Kehui Xie, Jianbin Wang, Rong Yang, Qiong Wu, Xiaoxue Pi, Hongzheng Fu*   

  1. 1. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Science, Peking University Health Science Center, Beijing 100191, China
    2. Department of Pharmaceutics, School of Medical Academy, Yangzhou University, Yangzhou 225009, China
  • Received:2012-11-28 Revised:2013-01-22 Online:2013-03-18 Published:2013-03-18
  • Contact: Hongzheng Fu*

Abstract:

One new ent-pimarane diterpenoid ent-16-nor-3-oxo-pimar-8(14)-en-15-al (1) together with four known diterpenoids kirenol (2), ent-2-oxo-15,16,19-trihydroxypimar-8(14)-ene (3), darutigenol (4) and darutoside (5) were isolated from the ethanol extract of Siegesbeckia pubescens. The planar structures and relative configurations of these compounds were elucidated by comprehensive spectroscopic analysis.

Key words: Siegesbeckia pubescens, Diterpenoids, Structural identification

CLC Number: 

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