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Chemical constituents from processed seeds of Strychnos nux-vomica

Jia-Yu Zhang, Ning Li, Kua Hu, Peng-Fei Tu*   

  1. State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing 100191, China
  • Received:2011-12-01 Revised:2012-02-02 Online:2012-03-15 Published:2012-03-15
  • Contact: Peng-Fei Tu*

Abstract:

Fifteen compounds were isolated from the processed seeds of Strychnos nux-vomica and were identified as follows: strychnine (1), brucine (2), pseudostrychnine (3), pseudobrucine (4), secoxyloganin (5), caffeic acid (6), p-hydroxybenzoic acid (7), p-hydroxyphenylacetic acid (8), uvaol (9), stigmasta-7,22,25-triene-3-ol (10), lupeol (11), 11-oxo-α-amyrin palmitate (12), catechol (13), maltol (14), adenosine (15). Compounds 5-15 were isolated from genus Strychnos for the first time.

Key words: Processed seeds of Strychnos nux-vomica, Chemical constituents, Structural identification

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