| [1] |
Park, K.S.; Chong, Y.; Kim, M.K. Myricetin: biological activity related to human health. Appl. Biol. Chem. 2016, 59, 259–269.
|
| [2] |
Kang, K.A.; Wang, Z.H.; Zhang, R.; Piao, M.J.; Kim, K.C.; Kang, S.S.; Kim, Y.W.; Lee, J.; Park, D.; Hyun, J.W. Myricetin protects cells against oxidative stress-induced apoptosis via regulation of PI3K/Akt and MAPK signaling pathways. Int. J. Mol. Sci. 2010, 11, 4348–4360.
|
| [3] |
Jomová, K.; Hudecova, L.; Lauro, P.; Simunkova, M.; Alwasel, S.H.; Alhazza, I.M.; Valko, M. A switch between antioxidant and prooxidant properties of the phenolic compounds myricetin, morin, 3',4'-dihydroxyflavone, taxifolin and 4-hydroxy-coumarin in the presence of copper (II) ions: a spectroscopic, absorption titration and DNA damage study. Molecules. 2019, 24, E4335.
|
| [4] |
Hou, W.; Hu, S.; Su, Z.; Wang, Q.; Meng, G.; Guo, T.; Zhang, J.; Gao, P. Myricetin attenuates LPS-induced inflammation in RAW 264.7 macrophages and mouse models. Future Med. Chem. 2018, 10, 2253–2264.
|
| [5] |
Zhu, S.F.; Yang, C.; Zhang, L.; Wang, S.X.; Ma, M.X.; Zhao, J.C.; Song, Z.Y.; Wang, F.; Qu, X.J.; Li, F.; Li, W.B. Development of M10, myricetin-3-O-β-d-lactose sodium salt, a derivative of myricetin as a potent agent of anti-chronic colonic inflammation. Eur. J. Med. Chem. 2019, 174, 9–15.
|
| [6] |
Li, G.; Wang, G.Z.; Si, X.S.; Zhang, X.K.; Liu, W.T.; Li, L.; Wang, J.F. Inhibition of suilysin activity and inflammation by myricetin attenuates Streptococcus suis virulence. Life Sci. 2019, 223, 62–68.
|
| [7] |
Singh, P.; Bast, F. Screening and biological evaluation of myricetin as a multiple target inhibitor insulin, epidermal growth factor, and androgen receptor; in silico and in vitro. Invest. New Drugs. 2015, 33, 575–593.
|
| [8] |
Ying, X.Z.; Chen, X.W.; Wang, T.; Zheng, W.H.; Chen, L.; Xu, Y.J. Possible osteoprotective effects of myricetin in STZ induced diabetic osteoporosis in rats. Eur. J. Pharmacol. 2020, 866, 172805.
|
| [9] |
Yao, Z.X.; Li, C.; Gu, Y.Q.; Zhang, Q.; Liu, L.; Meng, G.; Wu, H.M.; Bao, X.; Zhang, S.M.; Sun, S.M.; Wang, X.; Zhou, M.; Jia, Q.Y.; Song, K.; Li, Z.; Gao, W.N.; Niu, K.J.; Guo, C.J. Dietary myricetin intake is inversely associated with the prevalence of type 2 diabetes mellitus in a Chinese population. Nutr. Res. 2019, 68, 82–91.
|
| [10] |
Matić, S.; Stanić, S.; Bogojević, D.; Vidaković, M.; Grdović, N.; Dinić, S.; Solujić, S.; Mladenović, M.; Stanković, N.; Mihailović, M. Methanol extract from the stem of Cotinus coggygria Scop., and its major bioactive phytochemical constituent myricetin modulate pyrogallol-induced DNA damage and liver injury. Mutat. Res. Toxicol. Environ. Mutagen. 2013, 755, 81–89.
|
| [11] |
Kim, H.Y.; Park, S.Y.; Choung, S.Y. Enhancing effects of myricetin on the osteogenic differentiation of human periodontal ligament stem cells via BMP-2/Smad and ERK/JNK/p38 mitogen-activated protein kinase signaling pathway. Eur. J. Pharmacol. 2018, 834, 84–91.
|
| [12] |
Jiang, M.; Zhu, M.L.; Wang, L.; Yu, S.W. Anti-tumor effects and associated molecular mechanisms of myricetin. Biomed. Pharmacother. 2019, 120, 109506.
|
| [13] |
Li, M.J.; Chen, J.L.; Yu, X.F.; Xu, S.; Li, D.F.; Zheng, Q.S.; Yin, Y.C. Myricetin suppresses the propagation of hepatocellular carcinoma via down-regulating expression of YAP. Cells. 2019, 8, 358.
|
| [14] |
Basabe, P.; de Román, M.; Marcos, I.S.; Diez, D.; Blanco, A.; Bodero, O.; Mollinedo, F.; Sierra, B.G.; Urones, J.G. Prenylflavonoids and prenyl/alkyl-phloroacetophenones: Synthesis and antitumour biological evaluation. Eur. J. Med. Chem. 2010, 45, 4258–4269.
|
| [15] |
Knickle, A.; Fernando, W.; Greenshields, A.L.; Vasantha Rupasinghe, H.P.; Hoskin, D.W. Myricetin-induced apoptosis of triple-negative breast cancer cells is mediated by the iron-dependent generation of reactive oxygen species from hydrogen peroxide. Food Chem. Toxicol. 2018, 118, 154–167.
|
| [16] |
Kim, M.E.; Ha, T.K.; Yoon, J.H.; Lee, J.S. Myricetin induces cell death of human colon cancer cells via BAX/BCL2-dependent pathway. Anticancer Res. 2014, 34, 701–706.
|
| [17] |
Ma, L.; Cao, X.Q.; Wang, H.Y.; Lu, K.; Wang, Y.; Tu, C.H.; Dai, Y.J.; Meng, Y.Y.; Li, Y.Y.; Yu, P.; Man, S.L.; Diao, A.P. Discovery of myricetin as a potent inhibitor of human flap endonuclease 1, which potentially can be used as sensitizing agent against HT-29 human colon cancer cells. J. Agric. Food Chem. 2019, 67, 1656–1665.
|
| [18] |
Zhang, Q.Y.; Liu, J.; Liu, B.; Xia, J.; Chen, N.P.; Chen, X.F.; Cao, Y.; Zhang, C.; Lu, C.J.; Li, M.Y.; Zhu, R.Z. Dihydromyricetin promotes hepatocellular carcinoma regression via a p53 activation-dependent mechanism. Sci. Rep. 2014, 4, 4628.
|
| [19] |
Ye, C.; Zhang, C.; Huang, H.; Yang, B.; Xiao, G.G.; Kong, D.P.; Tian, Q.Q.; Song, Q.X.; Song, Y.J.; Tan, H.S.; Wang, Y.; Zhou, T.; Zi, X.Y.; Sun, Y.H. The natural compound myricetin effectively represses the malignant progression of prostate cancer by inhibiting PIM1 and disrupting the PIM1/CXCR4 interaction. Cell Physiol. Biochem. 2018, 48, 1230–1244.
|
| [20] |
Cui, W.; Zhang, J.; Wang, Q.; Gao, K.; Zhang, W.; Yang, J. A novel synthesis of naringenin and related flavanones. J. Chem. Res. 2014, 38, 686–689.
|
| [21] |
(a) Boers, F.; Deng, B.L.; Lemière, G.; Lepoivrea, J.; Groota, A.D.; Donunissea, R.; Vlietinck, A.J. An Improved Synthesis of the Anti-Picornavirus Flavone 3-O-Methylquercetin. Arch Pharm. 1997, 330, 313–316. (b) Dorman, G.; Prestwich, G.D. Benzophenone Photophores in Biochemistry. Biochemistry. 1994, 33, 5661–5673. (c) Fleming, S.A. Chemical reagents in photoaffinity labeling. Tetrahedron. 1995, 51, 12479–12520.
|
| [22] |
Yato, M.; Ohwada, T.; Shudo, K. Requirements for Houben-Hoesch and Gattermann reactions. Involvement of diprotonated cyanides in the reactions with benzene. J. Am. Chem. Soc. 1991, 113, 691–692.
|
| [23] |
Tsukayama, M.; Kusunoki, E.; Hossain, M.M.; Kawamura, Y.; Hayashi, S. Microwave-assisted efficient synthesis of polymethoxyacetophenones and natural polymethoxyflavones, and their inhibitory effects on melanogenesis. Heterocycles. 2007, 71, 1589.
|
| [24] |
Mateeva, N.N.; Kode, R.N.; Redda, K.K. Synthesis of novel flavonoid derivatives as potential HIV-Integrase inhibitors. J. Heterocycl. Chem. 2002, 39, 1251–1258.
|
| [25] |
Sarma, P.N.; Srimannarayana, G.; Subba Rao, N.V. Synthesis of naturally occurring partial methyl ethers of myricetin. Proc. Indian Acad. Sci. Sect. A. 1974, 80, 168–173.
|
| [26] |
Korul’kina, L.M.; Shul’ts, E.E.; Zhusupova, G.E.; Abilov, Z.A.; Erzhanov, K.B.; Chaudri, M.I. Biologically active compounds from Limonium Gmelinii and L. Popovii I. Chem. Nat. Compd. 2004, 40, 465–471.
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