[1] |
Chen, W.Q.; Zheng, R.S.; Baade, P.D.; Zhang, S.W.; Zeng, H.M.; Bray, F.; Jemal, A.; Yu, X.Q.; He, J. Cancer statistics in China, 2015. CA Cancer J. Clin. 2016, 66, 115–132.
|
[2] |
Tong, X.H.; Han, L.; Duan, H.Q.; Cui, Y.R.; Feng, Y.L.; Zhu, Y.M.; Chen, Z.; Yang, S.L. The derivatives of Pulsatilla saponin A, a bioactive compound from Pulsatilla chinensis: Their synthesis, cytotoxicity, haemolytic toxicity and mechanism of action. Eur. J. Med. Chem. 2017, 129, 325–336.
|
[3] |
Guo, X.Z.; Xie, Y.; Lian, S.; Li, Z.X.; Gao, Y.; Xu, Z.; Hu, P.; Chen, M.C.; Sun, Z.L.; Tian, X.T.; Huang, C.G. A sensitive HPLC-MS/MS method for the simultaneous determination of anemoside B4, anemoside A3 and 23-hydroxybetulinic acid: Application to the pharmacokinetics and liver distribution of Pulsatilla chinensis saponins. Biomed. Chromatogr. 2018, 32, e4124.
|
[4] |
Zheng, Y.T.; Zhou, F.; Wu, X.L.; Wen, X.Z.; Li, Y.N.; Yan, B.; Zhang, J.W.; Hao, G.; Ye, W.C.; Wang, G.J. 23-Hydroxybetulinic acid from Pulsatilla chinensis (Bunge) Regel synergizes the antitumor activities of doxorubicin in vitro and in vivo. J. Ethnopharmacol. 2010, 128, 615–622.
|
[5] |
Liang, Y.C.; Xu, X.J.; Yu, H.M.; Li, L.; Hong, T.; Ji, Q.B.; Feng, Y.L.; Jin, S.; Song, Y.Q.; Guo, J.; Zheng, Z.B.; Ye, Q.N.; Yang, S.L. Raddeanoside R13 inhibits breast cancer cell proliferation, invasion, and metastasis. Tumor Biol. 2016, 37, 9837–9847.
|
[6] |
Liu, M.; Zhao, X.Z.; Xiao, L.; Liu, G.; Liu, H.Z.; Wang, X.Y.; Feng, X.; Lin, X.K. Cytotoxicity of the compounds isolated from Pulsatilla chinensis saponins and apoptosis induced by 23-hydroxybetulinic acid. Pharm. Biol. 2015, 53, 1–9.
|
[7] |
Duan, Y.S.; Zhang, S.; Wang, L.L.; Zhou, X.; He, Q.H.; Liu, S.; Yue, K.; Wang, X.D. Targeted silencing of CXCR4 inhibits epithelial-mesenchymal transition in oral squamous cell carcinoma. Oncol. Lett. 2016, 12, 2055–2061.
|
[8] |
Pan, W.J.; Ding, L. Effects of Pulchinenoside at Different Concentrations on the Proliferation and Migration of Squamous Cell carcinoma cells and calpain-1, E-cadherin and N-cadherin protein. China Pharmacist. 2018, 21, 984–988.
|
[9] |
Goode, E.; Smyth, E. Immunotherapy for gastroesophageal cancer. J. Clin. Med. 2016, 5, 84.
|
[10] |
Guan, Z.Y.; Chen, L.Y.; Luo, Y.Y.; Cui, Y.R.; Shou, B.Y.; Zhou, L.F. Effect of Saponins in Pulsatillae Radix on Proliferation and Apoptosis of NCI-H460 Lung Cancer Cells and Screening of its Differentially Expressed Proteins. Chin. J. Exp. Med. Formul. 2019, 25, 49–56.
|
[11] |
Luo, Y.Y. Ph.D. thesis, Hunan University of Traditional Chinese Medicine. 2014.
|
[12] |
Yang, H.; Kim, H.; Kim, Y.C.; Sung, S.H. Cytotoxic activities of naturally occurring oleanane-, ursane-, and lupane-type triterpenes on HepG2 and AGS cells. Pharmacogn. Mag. 2017, 13, 118.
|
[13] |
Hong, S.W.; Jung, K.H.; Lee, H.S.; Son, M.K.; Yan, H.H.; Kang, N.S.; Lee, J.; Hong, S.S. SB365, Pulsatilla saponin D, targets c-Met and exerts antiangiogenic and antitumor activities. Carcinogenesis. 2013, 34, 2156–2169.
|
[14] |
Luo, Y.Y.; Yan, X.; Xie, X.X.; Wang, M.L.; Feng, Y.L.; Yang, S.L.; Li, J. Study on Antitumor Effect and Its Structure-Activity Relationship of Pulsatilla Saponin and Its Major Constituents. Mod. Chin. Med. 2018, 20, 791–796.
|
[15] |
Liang, C.Y. Ph.D. thesis, Beijing University of Traditional Chinese Medicine. 2016.
|
[16] |
Chen, L.Y.; Zhou, M.J.; Cui, Y.R.; Wang, H.L.; Guan, Z.Y.; Luo, Y.Y. Effect of Pulsatilla saponins on Glycolysis Pathway Inhibiting Proliferation of Colorectal Cancer Cells in SW480. J. Chin. Med. Materls. 2019, 42, 652–656.
|
[17] |
Cui, Y.R.; Wang, H.L.; Chen, L.Y.; Guan, Z.Y.; Luo, Y.Y. Effects of Pulsatilla Saponin A on key proteins and regulatory factor HIF-1α of glycolytic pathway in SW480 human colorectal cancer cells. Chin. Tradit. Patent Med. 2019, 41, 2887–2892.
|
[18] |
Li, M.; Fang, M.Z. Resistance reverse effect of anemoside B4 and tetrandrine on oxaliplatin-resistant human colon cancer cells and the mechanism. China Oncol. 2015, 25, 38–44.
|
[19] |
Bray, F.; Ferlay, J.; Soerjomataram, I.; Siegel, R.L.; Torre, L.A.; Jemal, A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J. Clin. 2018, 68, 394–424.
|
[20] |
Luo, Y.Y.; Chen, L.Y.; Jian, H.; Cui, Y.R.; Xie, X.X.; Liu, P.; Yang, S.L.; Guo, J.S. Regulation of saponins from Pulsatilla chinensis on energy metabolism of Bel-7402 xenograft in nude mice. Chin. Tradit. Herb Drug. 2014, 45, 973–977.
|
[21] |
Liu, Q.; Chen, W.C.; Jiao, Y.; Hou, J.Q.; Wu, Q.Y.; Liu, Y.L.; Qi, X.F. Pulsatilla saponin A, an active molecule from Pulsatilla chinensis, induces cancer cell death and inhibits tumor growth in mouse xenograft models. J. Surg. Res. 2014, 188, 387–395.
|
[22] |
Xue, S.Y.; Zhou, Y.; Zhang, J.; Xiang, Z.; Liu, Y.; Miao, T.; Liu, G.X.; Liu, B.G.; Liu, X.; Shen, L.X.; Zhang, Z.; Li, M.C.; Miao, Q. Anemoside B4 exerts anti-cancer effect by inducing apoptosis and autophagy through inhibiton of PI3K/Akt/mTOR pathway in hepatocellular carcinoma. Am. J. Transl. Res. 2019, 11, 2580–2589.
|
[23] |
Xue, S.Y.; Li, M.C.; Miao, Q.; Zhou, Y. Inhibitory Effects and Mechanism of Anemoside B4 on Hepatocellular Carcinoma Huh-7 Cells and Tumorbearing Nude Mice. China Pharm. 2019, 30, 601–607.
|
[24] |
Hong, S.W.; Jung, K.H.; Lee, H.S.; Choi, M.J.; Son, M.K.; Zheng, H.M.; Hong, S.S. SB365 inhibits angiogenesis and induces apoptosis of hepatocellular carcinoma through modulation of PI3K/Akt/mTOR signaling pathway. Cancer Sci. 2012, 103, 1929–1937.
|
[25] |
Xu, K.; Shu, Z.; Wang, Y.L.; Xu, Q.M.; Yang, S.L.; liu, Y.L. Effect of Pulsatilla saponin D on hepatocarcinoma in vivo and in vitro. Chin. Tradit. Patent Med. 2014, 36, 240–244.
|
[26] |
Yue, W.H.; Xu, K.; Feng, Y.L.; Zhang, T.; Xu, Q.M.; Yang, S.L.; Liu, Y.L. Antihepatocarcinoma effect in vitro of pulchinenoside D and mechanisms. Chin. Tradit. Herb Drug. 2014, 45, 3295–3301.
|
[27] |
Lei, Y.H. M.S. thesis, Jinan University. 2017.
|
[28] |
Wang, T.; Zhang, R.; Qi, X.F.; Bai, S.S.; Gong, F.; Chen, Z.X.; Cen, J.N.; Zhu, M.Q.; Dai, L. Differentiation of K562 cells induced by pulsatilla saponin A into erythroid lineage. Chin. J. Exp. Hematol. 2016, 24, 975–979.
|
[29] |
Wang, T. M.S. thesis, Suzhou University. 2015.
|
[30] |
Wang, T.; Gong, F.; Zhang, R.; Cen, J.N.; Dai, L.; Zhu, M.Q.; Qi, X.F. Pulsatilla saponin A induces differentiation in acute myeloid leukemia in vitro. Hematology. 2016, 21, 182–186.
|
[31] |
Zhang, Y.L.; Bao, J.; Wang, K.; Jia, X.; Zhang, C.; Huang, B.R.; Chen, M.; Wan, J.; Su, H.; Wang, Y.; He, C. Pulsatilla saponin D inhibits autophagic flux and synergistically enhances the anticancer activity of chemotherapeutic agents against HeLa cells. Am. J. Chin. Med. 2015, 43, 1657–1670
|
[32] |
Shain, K.H.; Dalton, W.S.; Tao, J. The tumor microenvironment shapes hallmarks of mature B-cell malignancies. Oncogene. 2015, 34, 4673–4682.
|
[33] |
Zhou, Y.Y. M.S. Thesis, Suzhou University. 2017.
|
[34] |
Mikawa, T.; LLeonart, M.E.; Takaori-Kondo, A.; Inagaki, N.; Yokode, M.; Kondoh, H. Dysregulated glycolysis as an oncogenic event. Cell Mol. Life Sci. 2015, 72, 1881–1892.
|
[35] |
Lim, M.C.; Lee, M.; Shim, S.H.; Nam, E.J.; Lee, J.Y.; Kim, H.J.; Lee, Y.Y.; Lee, K.B.; Park, J.Y.; Kim, Y.H.; Ki, K.D.; Song, Y.J.; Chung, H.H.; Kim, S.; Lee, J.W.; Kim, J.W.; Bae, D.S.; Lee, J.M. Practice guidelines for management of cervical cancer in Korea: a Korean Society of Gynecologic Oncology Consensus Statement. J. Gynecol. Oncol. 2017, 28, e22.
|
[36] |
Bhatla, N.; Aoki, D.; Sharma, D.N.; Sankaranarayanan, R. Cancer of the cervix uteri. Int. J. Gynecol. Obstet. 2018, 143, 22–36.
|
[37] |
Wang, B.; Chen, W.; Zhang, X.Y.; Yin, L.L. Antiproliferative effect of pulsatilla saponin D on cervical cancer cells and its relationship with Wnt signaling pathway. Chin. J. Clin. Pharmacol. 2019, 35, 2732–2735.
|
[38] |
Ren, N.N.; Duan, H.X.; Zhang, J.B. Study on Notch signaling pathway for mediating anti-cervical cancer effect of Anemoside B4 and its mechanism. Chongqing Med. J. 2020, 49, 705–708.
|
[39] |
Siegel, R.L.; Fedewa, S.A.; Miller, K.D.; Goding-Sauer, A.; Pinheiro, P.S.; Martinez-Tyson, D.; Jemal, A. Cancer statistics for hispanics/latinos, 2015. CA Cancer J. Clin. 2015, 65, 457–480.
|
[40] |
Wang, Y.E.; Yue, W.H.; Xu, Q.M.; Li, X.R.; Li, K.P. Antitumor effect and mechanism of pulchinenoside D on A549 tumor cells in vitro. J. Guangdong Pharm. Univ. 2018, 34, 316–319.
|
[41] |
Jang, W.J.; Park, B.; Jeong, G.S.; Hong, S.S.; Jeong, C.H. SB365, Pulsatilla saponin D, suppresses the growth of gefitinib-resistant NSCLC cells with Met amplification. Oncol. Rep. 2014, 32, 2612–2618.
|
[42] |
Siegel, R.L.; Miller, K.D.; Jemal, A. Cancer statistics, 2017. CA Cancer J. Clin. 2017, 67, 7–30.
|
[43] |
Liang, Y.C.; Xu, X.J.; Yu, H.M.; Li, L.; Hong, T.; Ji, Q.B.; Feng, Y.L.; Jin, S.; Song, Y.Q.; Guo, J.; Zheng, Z.B.; Ye, Q.N.; Yang, S.L. Raddeanoside R13 inhibits breast cancer cell proliferation, invasion, and metastasis. Tumor Biol. 2016, 37, 9837–9847.
|
[44] |
Feng, X.L.; Liu, D. Effect of pulchinenoside D on the Wnt/β-catenin signaling pathway in human breast carcinoma cell lines MCF-7. J. Southeast Univ. 2017, 36, 379–383.
|
[45] |
Hu, C.; Yue, W.H.; Peng, C.P.; Xu, Q.M.; Li, X.R.; Yang, S.L.; Wang, Y.L.; Liu, Y.L. Antitumor Effects of Pulsatilla Saponin D on MCF-7 Tumor Cells in Vitro and in Vivo. Tradit. Chin. Drug Res.Clin. Pharmacol. 2017, 28, 418–423.
|
[46] |
Zou, X.J.; Hao, Y.Y.; Hu, Y.D.; Xie, M.X.; Bai, W. Pulsatilla saponin A affects proliferation and radiosensitivity of breast cancer cells by regulating miR-24-3p/RNF2 expression. Chin. J. Pathophysiol. 2020, 36, 865–870.
|
[47] |
Yan, J.; Xu, C.H.; Li, Y.P.; Tang, B.; Xie, S.H.; Hong, T.; Zeng, E.M. Long non-coding RNA LINC00526 represses glioma progression via forming a double negative feedback loop with AXL. J. Cell Mol. Med. 2019, 23, 5518–5531.
|
[48] |
Peng, C.P.; Xu, Q.M.; Zhan, T. Li, X.R.; Yang, S.L.; Zhou,Y.; Liu, Y.L. Anti-glioma Effect and Mechanism of Alkali Hydrolysate of Total Saponins from Pulsatilla chinensis on Human Glioma U251 Cells. Tradit. Chin. Drug Res. Clin. Pharmacol. 2014, 25, 254–259.
|
[49] |
Li, B.; Wang, Y.G.; Li, J.; Tang, H.F.; Chen, G. Pulsatilla saponin D induces cell apoptosis in the U87MG cells. Basic Clini. Med. 2014, 34, 654–660.
|
[50] |
Li, B. M.S. thesis, Fourth Military Medical University. 2014.
|
[51] |
Rastrelli, M.; Tropea, S.; Rossi, C.R.; Alaibac, M. Melanoma: epidemiology, risk factors, pathogenesis, diagnosis and classification. Vivo. 2014, 28, 1005–1011.
|
[52] |
Wu, M.L.; Luo, Y.Y.; Yan, X.; Chen, L.Y.; Cui, Y.R.; Liu, P.; Xie, X.X.; Yu, J. Preliminary study on the effect and Mechanism of Pulsatilla officinalis saponins on inflammatory factors in B16-F10 melanoma-bearing mice. Chin. Tradit. Patent Med. 2020, 42, 1609–1614.
|