白花丹地上部分的化学成分

白花丹地上部分的化学成分

黄小燕, 谭明雄, 吴强, 陈勇, 王恒山^*

广西师范大学化学化工学院药用资源化学与药物分子工程重点实验室, 广西桂林 541004

收稿日期:2008-02-21 修回日期:2008-05-10 出版日期:2008-06-15 发布日期:2008-06-15
通讯作者: 王恒山*

Chemical constituents from the aerial parts of Plumbago zeylanica L.

Xiao-Yan Huang, Ming-Xiong Tan, Qiang Wu, Yong Chen, Heng-Shan Wang^*

Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, College of Chemistry & Chemical Engineering, Guangxi Normal University, Guilin 541004, China

Received:2008-02-21 Revised:2008-05-10 Online:2008-06-15 Published:2008-06-15
Contact: Heng-Shan Wang*

摘要/Abstract

摘要：

研究白花丹Plumbago zeylanica L. 地上部分的化学成分。应用各种色谱方法分离; 用波谱学方法特别是二维核磁共振波谱的方法确定结构。从白花丹地上部分分离鉴定了7个化合物, 分别是: 1β,3β,11α-trihydroxy-urs-12-ene (1), androsta-1,4-diene-3,17-dione (2), 异信浓柿醇酮 (3), neoechinulin A (4), harman (5), ergostadiene-3β,5α,6β-triol (6), N-(N-benzoyl-S-phenylalaninyl)-S-phenylalaninol (7)。化合物1 为新化合物, 化合物2, 4–7 均为首次从该属植物中分离得到。

关键词: 白花丹属, 白花丹属, 白花丹属, 白花丹, 白花丹, 白花丹, 化学成分, 化学成分, 化学成分, , ,

Abstract:

To investigate the chemical constituents from the aerial parts of Plumbago zeylanica L. The chemical constituents were isolated by various column chromatographic methods and the structures were elucidated by various spectroscopic methods, especially 2D NMR spectra. A new triterpenoid, 1β,3β,11α-trihydroxy-urs-12-ene (1), together with six known compounds, androsta-1,4-diene-3,17- dione (2), isoshinznolone (3), neoechinulin A (4), harman (5), ergostadiene-3β,5α,6β-triol (6) and N-(N'-benzoyl-S-phenylalaninyl)-Sphenylalaninol (7) were isolated from the aerial parts of P. zeylanica. Compound 1 was a new compound, and compounds 2, 4-7 were obtained from this genus for the first time.

Key words: Plumbago, Plumbago, Plumbago zeylanica L., Plumbago zeylanica L., Chemical constituents, Chemical constituents, ,

中图分类号:

R284.1

Supporting: This study was supported by 973 project (Grant No. 2007CB-516805), the Natural Science Foundation of Guangxi Province (05112001-3B2) and the Project of the Key Laboratory of Medicinal Chemical Resources and Molecular Engineering Guangxi Normal University, (Grant No. 0630006-5D09).

黄小燕, 谭明雄, 吴强, 陈勇, 王恒山^*.

白花丹地上部分的化学成分

[J]. .

Xiao-Yan Huang, Ming-Xiong Tan, Qiang Wu, Yong Chen, Heng-Shan Wang^*. Chemical constituents from the aerial parts of Plumbago zeylanica L.[J]. .

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