刺桐中黄酮类成分研究

doi:10.5246/jcps.2024.07.049

中国药学(英文版) ›› 2024, Vol. 33 ›› Issue (7): 659-665.DOI: 10.5246/jcps.2024.07.049

• 【研究论文】 • 上一篇

刺桐中黄酮类成分研究

高勇春, 杨茜, 王利勤^*()

云南师范大学化学化工学院, 云南昆明 650500

收稿日期:2023-12-03 修回日期:2024-01-06 接受日期:2024-03-06 出版日期:2024-07-30 发布日期:2024-07-30
通讯作者: 王利勤

Flavonoid from the twigs and leaves of Erythrina variegata

Yongchun Gao, Xi Yang, Liqin Wang^*()

School of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650500, Yunnan, China

Received:2023-12-03 Revised:2024-01-06 Accepted:2024-03-06 Online:2024-07-30 Published:2024-07-30
Contact: Liqin Wang
Supported by:
National Natural Science Foundation of China (Grant No. 32060099).

摘要/Abstract

摘要：

本研究采用硅胶柱色谱, 凝胶Sephadex LH-20 柱色谱和反相MCI柱色谱技术对刺桐Erythrina variegata的乙醇提取物进行化学成分的分离纯化, 得到17个黄酮类化合物, 包括9个异戊烯基取代的异黄酮、4个简单的异黄酮、3个二氢黄酮和1个黄酮。通过核磁共振波谱数据分析和文献对照, 将它们的结构鉴定为: euchrenone b₁₀ (1), senegalensin (2), erythrinin C (3), scandenone (4), osajin (5), alpinumisoflavone (6), isoerysenegalensein E (7), erysenegalensein E (8), diprenylgenistein (9), abyssinone V (10), abyssinone V 4′-methyl ether (11), 4′,7-二羟基二氢黄酮 (12), 红车轴草素 (13), 2′,4′,5,7-四羟基异黄酮 (14), 染料木素 (15), 黄豆苷元 (16)和芹菜素 (17)。除化合物1, 4–7, 9–10外, 其余化合物均首次从刺桐中分离得到。

关键词: 刺桐属, 刺桐, 异戊烯基异黄酮, 异黄酮

Abstract:

In the present study, 17 flavonoids, including 9 prenylated isoflavones, 4 isoflavones, 3 flavanones and 1 flavone, were isolated from the twigs and leaves of Erythrina variegata. By NMR spectroscopic means and comparision with the data in the leteratures, their structures were elucidated to be euchrenone b₁₀(1), senegalensin (2), erythrinin C (3), scandenone (4), osajin (5), alpinum isoflavone (6), isoerysenegalensein E (7), erysenegalensein E (8), diprenylgenistein (9), abyssinone V (10), abyssinone V 4′-methyl ether (11), 4′,7-dihydroxyflavanone (12), 3′,5,7-trihydroxy-4′-methoxyisoflavone (13), 2′,4′,5,7-tetrahydroxyisoflavone (14), genistein (15), daidzein (16), and apigenin (17). Except for compounds 1, 4–7, and 9–10, other compounds were isolated from E. variegata for the first time.

Key words: Erythrina variegata, Erythrina, Prenylated isoflavone, Isoflavone

Supporting:

高勇春, 杨茜, 王利勤. 刺桐中黄酮类成分研究[J]. 中国药学(英文版), 2024, 33(7): 659-665.

Yongchun Gao, Xi Yang, Liqin Wang. Flavonoid from the twigs and leaves of Erythrina variegata[J]. Journal of Chinese Pharmaceutical Sciences, 2024, 33(7): 659-665.

图/表 1

参考文献 19

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刺桐中黄酮类成分研究

Flavonoid from the twigs and leaves of Erythrina variegata

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