http://jcps.bjmu.edu.cn

中国药学(英文版) ›› 2019, Vol. 28 ›› Issue (7): 519-526.DOI: 10.5246/jcps.2019.07.049

• 【 其 它 】 • 上一篇    

高校仪器共享平台电子顺磁共振波谱仪的管理

许迎利, 白光灿, 卢景雰*   

  1. 北京大学医学部 药学院 天然药物及仿生药物国家重点实验室, 北京 100191
  • 收稿日期:2019-05-12 修回日期:2019-06-13 出版日期:2019-07-31 发布日期:2019-06-20
  • 通讯作者: Tel.: +86-010-82802724, E-mail: yinglixu@bjmu.edu.cn; zdsljf@bjmu.edu.cn

Management of electron paramagnetic resonance spectrometer in a university core laboratory

Yingli Xu, Guangcan Bai, Jingfen Lu*   

  1. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China
  • Received:2019-05-12 Revised:2019-06-13 Online:2019-07-31 Published:2019-06-20
  • Contact: Tel.: +86-010-82802724, E-mail: yinglixu@bjmu.edu.cn; zdsljf@bjmu.edu.cn

摘要:

电子顺磁共振(Electron Paramagnetic Resonance, EPR)是唯一一种直接检测顺磁性物质的波谱学方法。EPR技术可以实现固体、液体、气体、细胞、活体样品中的自由基及过渡金属的定性定量分析, 广泛应用于化学、材料学、生命科学、量子物理等学科。本文以北京大学医学部天然药物及仿生药物国家重点实验室仪器平台电子顺磁共振波谱仪(德国Bruker A-200)为例, 从基本原理、设备构造、操作过程中应注意的问题、运行管理等方面进行了探讨, 使该仪器可以更好的为科研服务。

关键词: 电子顺磁共振波谱仪, 操作注意问题, 运行管理

Abstract:

Electron Paramagnetic Resonance (EPR) is the only spectral method for direct detection of paramagnetic substances. EPR technology can be used for the qualitative and quantitative analysis of free radicals and transition metals in solid, liquid, gas, cell and living samples. It is widely used in chemistry, material science, life science, quantum physics and other researches. This report discusses the basic principle, instrument structure, common problem solving, daily maintenance, and management model of the electron paramagnetic resonance spectrometer (German Bruker A-200) in the State Key Laboratory of Natural and Biomimetic Drugs of Peking University Health Science Center, so that the instrument can be fully used for various scientific researches.

Key words: Electron paramagnetic resonance spectrometer, Operational attention problem, Instrument maintenance

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