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Flavanoids and xanthones isolated from Arenaria serpyllifolia L.

Guanshen Zhou, Xiaojuan Yang, Yong Jiang*, Pengfei Tu   

  1. State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing 100191, China
  • Received:2012-10-20 Revised:2013-02-23 Online:2013-05-08 Published:2013-05-08
  • Contact: Yong Jiang*

Abstract: Eight known compounds were isolated from the whole plants of Arenaria serpyllifolia L. by solvent fractionation and subsequent separations with silica gel, ODS, Sephadex LH-20 and semi-preparative HPLC chromatography. Their structures were determined by spectroscopic analysis and identified as quercetin (1), quercetin 7-O-α-L-rhamnoside (2), quercetin 3-O-α-L-rhamnoside (3), 3-O-methyl quercetin (4), 1,5-dihydroxyxanthone (5), 1,5-dihydroxyxanthone-6-O-β-D-glucoside (6), 5-hydroxy-1-methoxyxanthone (7) and 6-deoxyisojacareubin (8). All these compounds were isolated from this title plant for the first time, and compounds 5-8 were obtained from genus Arenaria for the first time

Key words: Arenaria serpyllifolia L., Chemical constituents, Flavonoids, Xanthones

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