Chemical constituents from the aerial parts of Waltheria indica Linn.

doi:10.5246/jcps.2019.07.045

Abstract

Abstract:

A phytochemical investigation on the aerial parts of Waltheria indica Linn. led to the isolation of 16 compounds,including five terpenoids (1–5), four coumarins (6–9), six flavonoids (10–15), and one phenylpropanoid glycoside (16). The structuresof these compounds were identified by spectroscopic data analysis and comparison with those reported in the literatures. Except for12 and 15, all the compounds were isolated from W. indica for the first time. Moreover, coumarins were firstly reported to be obtained from this herb. The NO production inhibitory activities of all the isolated compounds in LPS-induced BV-2 cells were also presented.

Key words: Waltheria indica, Terpenoids, Flavonoids, Coumarins, NO production inhibitory activities

CLC Number:

R284

Supporting:

Yiming Hua, Xiaowen Zhang, Kewu Zeng, Qingying Zhang, Pengfei Tu. Chemical constituents from the aerial parts of Waltheria indica Linn.[J]. Journal of Chinese Pharmaceutical Sciences, 2019, 28(7): 468-475.

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