Cancer chemotherapy with novel bioactive natural products

doi:10.5246/jcps.2022.08.050

Abstract

Abstract:

Cancer is the primary cause of death on a global scale. Every year, 8.8 million people die because lung, prostate gland, colorectal, and hepatic cancers are more common in men. In contrast, mammary glands, large intestine, bronchi, cervix, and abdomen cancers are more common in women. The Food and Drug Administration of the United States of America has approved plant-based medications for cancer treatment. Examples include taxanes, such as paclitaxel, and vinca alkaloids, such as vincristine and vinblastine. Although, developing new anti-cancer medicine to treat this disease will necessitate a diverse range of bioactive sources. More than 30 natural compounds derived from plants have been identified, with clinical trials currently underway. According to a literature review of numerous publications and manuals, novel medicinal compounds derived from bioactive sources have been confirmed scientifically efficacious against many kinds of cancer cells. The current study focused on new therapeutic compounds extracted from the plants indicated to have antineoplastic effects in clinical trials. The most significant discoveries of these active new medicinal substances were also summarized and discussed.

Key words: Alkaloids, Glycosides, Antitumar, Anticancer, Terpenoids

Supporting:

Neha Dangi, Shikha Sharma. Cancer chemotherapy with novel bioactive natural products[J]. Journal of Chinese Pharmaceutical Sciences, 2022, 31(8): 589-607.

Figures/Tables 31

References 101

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