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Journal of Chinese Pharmaceutical Sciences ›› 2017, Vol. 26 ›› Issue (5): 317-334.DOI: 10.5246/jcps.2017.05.034

• Review •     Next Articles

Phytochemistry and bioactivities of sesquiterpenoids from the Artemisia species

Laibin Zhang1, Jinao Duan2, Jieli Lv1*   

  1. 1. School of Pharmacy, Xinxiang Medical University, Xinxiang 453003, China
    2. Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, Nanjing 210023, China
  • Received:2017-03-07 Revised:2017-04-25 Online:2017-05-26 Published:2017-05-28
  • Contact: Tel.: +86-0373-3831652, E-mail: jielilv2009@xxmu.edu.cn
  • Supported by:

    National Natural Science Foundation of China (Grant No. 31400305 and 81202916), the Science and Technology Project of Henan Province (Grant No. 152102310113), the Science and Technology Project of the Education Department of Henan Province (Grant No. 14A360012), and the Project for Youth Backbone Teachers in the University of Henan Province (Grant No. 2015GGJS-130).

Abstract:

The genus Artemisia is one of the largest and most widely distributed genera of the family Compositae. One type of the mainly active metabolites found in the Artemisia plants is sesquiterpenoids with extensive biological activities, including anti-inflammatory, immunomodulatory, anti-tumour, antimalarial, antinociceptive, antimicrobial and other activities. In this review, wecomprehensively summarized the progressconcerning the phytochemistry and biological activities of sesquiterpenoids obtained from the Artemisiaspecies from 2010 to July 2016. Furthermore,several future research perspectives and development of sesquiterpenoids as potential therapeutic agents were discussed as well.

Key words: Artemisia, Sesquiterpenoids, Phytochemsitry, Bioactivities

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