Sesquiterpenes from the aerial parts of Artemisia vestita Wall.

doi:10.5246/jcps.2013.06.077

Abstract

Abstract:

A chemical investigation of the aerial parts of Artemisia vestita Wall. led to the isolation of 12 known sesquiterpenes, including 2 furan-containing sesquiterpenoids and 10 eudesmane sesquiterpene lactones. Their structures were identified as negunfurol (1), schensianol A (2), artemine (3), erivanin (4), 1,5-diepi-artemin (5), acetylartemin (6), naphtho[1,2-b]furan-2(3H)-one, 6-(acetyloxy)decahydro-9a-hydroxy-3,5a-dimethyl-9-methylene-(3S,3aS,5aS,6S,9aS,9bS) (7), naphtho[1,2-b]furan-2(3H)-one, 6-(acetyloxy)-3a,4,5,5a,6,7,8,9b-octahydro-8-hydroxy-3,5a,9-trimethyl- (3S,3aS,5aR,6S,8S,9bS) (8), isoerivanin (9), barrelierin (10), (11S)-1-oxoeudesm-4(14)-eno-13,6α-lactone (11), 1-epi-dehydroisoeranin (12), respectively. All of these compounds were isolated from Artemisia vestita for the first time, and compounds 1 and 2 were isolated from the genus Artemisia for the first time.

Key words: Artemisia vestita, Sesquiterpene lactones, Eudesmane, Furan-containing sesquiterpenoid, Chemical constituents

CLC Number:

R284

Supporting:

Shuaihua Tian, Helin Wei, Mingbo Zhao, Chen Zhang, Pengfei Tu^* . Sesquiterpenes from the aerial parts of Artemisia vestita Wall.[J]. Journal of Chinese Pharmaceutical Sciences, DOI: 10.5246/jcps.2013.06.077.

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Sesquiterpenes from the aerial parts of Artemisia vestita Wall.

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