尿素包合与柱层析相结合从紫草油中分离高纯度亚麻酸

尿素包合与柱层析相结合从紫草油中分离高纯度亚麻酸

韩喜江^*, 徐平, 孟祥丽, 梁志华, 张宗双, 杨占成

哈尔滨工业大学应用化学系, 哈尔滨 150001

收稿日期:2003-01-08 修回日期:2004-02-10 出版日期:2004-03-15 发布日期:2004-03-15
通讯作者: 韩喜江*

Preparation of High-Purity Linolenic Acid from Oil of Lithospermum Erythrorhizon by Urea Inclusion and Column Chromatography

HAN Xi-jiang^*, XU Ping, MENG Xiang-li, LIANG Zhi-hua, ZHANG Zong-shuang, YANG Zhan-cheng

Department of Applied Chemistry, Harbin Institute of Technology, Harbin Heilon gjiang 150001, China

Received:2003-01-08 Revised:2004-02-10 Online:2004-03-15 Published:2004-03-15
Contact: HAN Xi-jiang*

摘要/Abstract

摘要： 目的从中国东北地区产的紫草油中提取高浓度亚麻酸. 方法采用尿素包合法和柱层析法. 结果分离得到了不饱和脂肪酸, 其中亚麻酸含量为99.30 wt%. 结论实验重现性好, 工业化生产的可行性较高.

关键词: 紫草油, 亚麻酸, 尿素包合, 柱层析

Abstract: Aim To separate high purity linolenic acid from the oil of Lithospermum erythrorhizon growing in the Northeast of China. Methods Urea inclusion and column chromatography were used. Results Unsaturated fatty acid was separated, with a purity of 99.30 wt% of linolenic acid. Conclusion The experiment shows excellent reproducibility and high feasibility for industrial production.

Key words: Lithospermum erythrorhizon, Lithospermum erythrorhizon, linolenic acid, linolenic acid, urea inclusion, urea inclusion, column chromatography, column chromatography

中图分类号:

R917

R284.2

Supporting: Foundation item: Heilongjiang Science and Technology Bureau (GG01C405-03).
^*Corresponding author: Fax: 86-451-6418750
Biograph: Dean of Chemistry Laboratory Center and professor in the Department of Chemistry of Harbin Institute of Technology.

韩喜江^*, 徐平, 孟祥丽, 梁志华, 张宗双, 杨占成. 尿素包合与柱层析相结合从紫草油中分离高纯度亚麻酸[J]. .

HAN Xi-jiang^*, XU Ping, MENG Xiang-li, LIANG Zhi-hua, ZHANG Zong-shuang, YANG Zhan-cheng . Preparation of High-Purity Linolenic Acid from Oil of Lithospermum Erythrorhizon by Urea Inclusion and Column Chromatography[J]. .

[1]	蒋蕾, 涂渝娇, 代伟华, 袁琳. 云南美登木愈伤组织化学成分的研究[J]. 中国药学(英文版), 2023, 32(4): 283-290.
[2]	刘少静, 秦蓓, 韩红芳, 李立, 余丽丽, 徐小静. 硅胶柱层析和半制备液相色谱法从曲克芦丁母液中分离制备高纯度曲克芦丁及有关物质[J]. 中国药学(英文版), 2020, 29(7): 487-493.
[3]	章良, 李虹, 吴梧桐^*. 中国皖南尖吻蝮蛇毒中细胞毒素的分离纯化和抗癌活性研究[J]. , 2004, 13(2): 97-102.