中国中老年癌症幸存者健康状况分析

doi:10.5246/jcps.2023.09.061

摘要/Abstract

摘要：

中国癌症幸存者的数量正在不断增长, 这一人群的健康问题是我国卫生系统所面临的一项严峻挑战。本研究概述了中国中老年癌症幸存者的健康状况, 并探究癌症史与健康状况之间的关系。本研究基于中国健康与养老追踪调查(CHARLS)数据识别癌症幸存者和无癌症史的受访者, 利用2018年的调查数据评估两组患者的自评健康状况、抑郁状况和日常生活活动能力并采用卡方检验和Logistic回归进行组间分析。本研究纳入了447名癌症幸存者和19 051名没有癌症史的受访者。与无癌症史的受访者相比, 癌症幸存者的自评健康状况更差、抑郁和日常生活活动能力受损的比例也更高。在调整了受访者的社会人口学特征和疾病与健康行为之后, 我们发现癌症史与更糟糕的自评健康状况 (OR 1.62; 95% CI, 1.38–1.96, P < 0.001)、更高的抑郁风险(OR 1.21; 95% CI, 1.10–1.34, P < 0.001)和日常生活活动能力受损(OR 1.43; 95% CI, 1.29–1.58, P < 0.001)显著相关。研究表明, 我国45岁以上癌症幸存者的生理和心理健康状况较差, 需要为他们提供更周到的支持与照顾。

关键词: 癌症幸存者, 健康状况, 抑郁, 中国健康与养老追踪调查

Abstract:

There is a growing population of cancer survivors, and their health poses a significant challenge for the Chinese healthcare system. However, research related to this topic remains limited. In the present study, we presented an overview of the health status of middle-aged and elderly cancer survivors in China and investigated the association between cancer history and health status. To conduct our research, we utilized data from the China Health and Retirement Longitudinal Study (CHARLS), where we identified cancer survivors and individuals without a history of cancer. We evaluated the self-reported health, depression levels, and activities of daily living of both groups using survey data collected in 2018. We performed intergroup analysis using chi-squared tests and logistic regression. The analysis included 447 cancer survivors and 19 051 respondents without a history of cancer. In comparison to those without cancer history, cancer survivors exhibited higher rates of poor health (90.2% vs. 76.6%, P < 0.001), depression (43.6% vs. 34.3%, P < 0.001), and inadequate daily activities (46.5% vs. 29.1%, P < 0.001). After adjusting for respondents’ demographic characteristics, disease status, and health behaviors, we found that a history of cancer was significantly associated with worse self-reported health (OR 1.62; 95% CI, 1.38–1.96, P < 0.001), a higher risk of depression (OR 1.21; 95% CI, 1.10–1.34, P < 0.001), and insufficient activities of daily living (OR 1.43; 95% CI, 1.29–1.58, P < 0.001). Our findings indicated that cancer survivors aged over 45 in China experience poorer physical and psychological conditions, underscoring the need for considerate support and care.

Key words: Cancer survivors, Health status, Depression, CHARLS

Supporting:

杜浩鑫, 保琦, 李黄倩玉, 张逸晨, 海沙尔江·吾守尔, 史录文, 管晓东. 中国中老年癌症幸存者健康状况分析[J]. 中国药学(英文版), 2023, 32(9): 744-754.

Haoxin Du, Qi Bao, Huangqianyu Li, Yichen Zhang, Haishaerjiang Wushouer, Luwen Shi, Xiaodong Guan. Health status of middle-aged and elderly cancer survivors in China[J]. Journal of Chinese Pharmaceutical Sciences, 2023, 32(9): 744-754.

图/表 2

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