Phytochemistry and pharmacological activities of Ficus carica latex: a systematic review

doi:10.5246/jcps.2022.02.007

摘要/Abstract

摘要：

Ficus carica tree produces a white sap that is traditionally used for the treatment of skin conditions, such as warts. Ficus carica latex is considered a rich source of proteins and metabolites that have various pharmacological activities. Most of the latex pharmacological activities are attributed to its phenolic content, such as anticancer, antiviral, antioxidant, anti-angiogenic, hepatoprotective, and wound-healing activities. Moreover, Ficus carica latex contains proteases that are involved in the treatments of skin conditions, such as warts, and display antiparasitic activity. Additionally, chitinase enzymes and coumarins are isolated from Ficus carica latex and involved in the antimicrobial activities of latex.

关键词: Latex, Ficus carica, Moraceae, Proteases, Ficin

Abstract:

Key words: Latex, Ficus carica, Moraceae, Proteases, Ficin

Supporting:

Haneen Mohammad, Muhammed Alzweiri. Phytochemistry and pharmacological activities of Ficus carica latex: a systematic review[J]. 中国药学(英文版), 2022, 31(2): 81-96.

Haneen Mohammad, Muhammed Alzweiri. Phytochemistry and pharmacological activities of Ficus carica latex: a systematic review[J]. Journal of Chinese Pharmaceutical Sciences, 2022, 31(2): 81-96.

图/表 4

Figure 1. Schematic representation of proteins and metabolites isolated from Ficus carica latex.

Figure 2. The chemical structures of phenolic compounds isolated from Ficus carica latex.

Figure 3. Schematic representation of the different pharmacological activities of Ficus carica latex and the responsible phytochemicals and proteins.

Table 1. Reported anticancer activities of Ficus carica latex and its IC50a values.

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