掺杂型超顺磁性氧化铁纳米簇的微波辅助制备及体外表征

doi:10.5246/jcps.2020.03.013

摘要/Abstract

摘要：

为了获得具有高饱和磁化强度的超顺磁性纳米材料, 本研究成功通过微波辅助溶剂热法制备出锰掺杂和锌掺杂的超顺磁性氧化铁纳米簇(Mn-doped or Zn-doped ferrite nanoclusters, Mn-FNs or Zn-FNs), 并利用透射电子显微镜(transmission electron microscopy, TEM)和动态光散射(dynamic light scattering, DLS)粒度仪对两者进行了初步的形态观察和粒径测定。之后, 选择形态和分散性更好的Zn-FNs, 进一步采用X射线衍射仪(X-ray diffractometer, XRD)、电感耦合等离子体质谱仪(inductively coupled plasma-mass spectrometry, ICP-MS)和振动样品磁强计(vibrating sample magnetometer, VSM)分别对其晶体结构、金属含量和磁学性质进行了体外表征。结果表明, Zn-FNs是由多个纳米粒子组装形成的团簇结构, 形态圆整, 分散性良好, 粒径较均一, 锌成功掺杂进入Zn-FNs中, 晶体具有尖晶石结构, 磁学性质优良。因此, Zn-FNs作为一种新型磁性纳米材料, 具有良好的应用前景。

关键词: 微波辅助溶剂热法, 掺杂型氧化铁纳米簇, 体外表征

Abstract:

In order to obtain nanomaterials with superparamagnetism and high saturation magnetization, Mn-doped or Zn-doped superparamagnetic ferrite nanoclusters (Mn-FNs or Zn-FNs) were prepared by microwave-assisted solvothermal method in this study. Preliminary investigations were performed by transmission electron microscopy (TEM) and dynamic light scattering (DLS) instrument to observe the morphology and measure the particle size, respectively. Afterwards, Zn-FNs were chosen to be further characterized in vitro due to their better morphology and dispersity than Mn-FNs. The subsequent characterizations included crystallinephase, metal content and magnetic properties by X-ray diffractometer (XRD), inductively coupled plasma-mass spectrometry (ICP-MS) and vibrating sample magnetometer (VSM), respectively. The results showed that Zn-FNs had a cluster-like structure assembled by multiple nanoparticles. Zn-FNs were spherical in shape with good dispersity and relatively uniform particle size. Zn was successfullydoped in Zn-FNs which demonstrated spinel structure and excellent magnetic properties. Therefore, Zn-FNs had a favorable application prospect as a new type of magnetic nanomaterial.

Key words: Microwave-assisted solvothermal method, Doped ferrite nanoclusters, In vitro characterizations

中图分类号:

R943

Supporting:

刘晓昕, 覃小雅, 李子圆, 范田园. 掺杂型超顺磁性氧化铁纳米簇的微波辅助制备及体外表征[J]. 中国药学(英文版), 2020, 29(3): 153-160.

Xiaoxin Liu, Xiaoya Qin, Ziyuan Li, Tianyuan Fan. Microwave-assisted preparation and in vitro characterizations of doped superparamagnetic ferrite nanoclusters[J]. Journal of Chinese Pharmaceutical Sciences, 2020, 29(3): 153-160.

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