http://jcps.bjmu.edu.cn

中国药学(英文版) ›› 2019, Vol. 28 ›› Issue (3): 209-215.DOI: 10.5246/jcps.2019.03.021

• 【研究论文】 • 上一篇    下一篇

中国药学综合性实验教学与实践

王超1, 王煦1, 赵帼英2, 王桂玲1, 张建国1, 胡新1, 叶敏3, 徐萍4*   

  1. 1. 北京大学医学部 药学院 药学实验教学中心, 北京 100191
    2. 北京大学医学部 药学院 教学办公室, 北京 100191
    3. 北京大学医学部 药学院 天然药物学系, 北京 100191
    4. 北京大学医学部 药学院 药物化学系, 北京 100191
  • 收稿日期:2019-01-15 修回日期:2019-02-28 出版日期:2019-03-30 发布日期:2019-03-01
  • 通讯作者: Tel.: +86-010-82802632, E-mail: pingxu@bjmu.edu.cn
  • 基金资助:

    The Education and Teaching Research Project of Peking University Health Science Center.

Teaching and practice of pharmaceutical comprehensive study in China

Chao Wang1, Xu Wang1, Guoying Zhao2, Guiling Wang1, Jianguo Zhang1, Xin Hu1, Min Ye3, Ping Xu4*   

  1. 1. Pharmaceutical Experimental Teaching Center, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China
    2. Office of education, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China
    3. Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China
    4. Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China
  • Received:2019-01-15 Revised:2019-02-28 Online:2019-03-30 Published:2019-03-01
  • Contact: Tel.: +86-010-82802632, E-mail: pingxu@bjmu.edu.cn
  • Supported by:

    The Education and Teaching Research Project of Peking University Health Science Center.

摘要:

药学综合性实验整合多个学科的药学知识, 覆盖新药研发的基本流程, 是中国实验教学的新体系。我们为探索该实验教学模式和体系的可行性, 以限选课的形式开设了药学综合性实验课程。本课程分为药学综合性实验设计(PCD)药学综合性实验(PCE)两部分。PCD部分包括文献综述、综合性实验设计及展示。PCE部分包括合成、含量测定、药效学研, 制剂及其质量评价。课程成绩由实验操作、报告、综述、综合实验设计及展示等部分成绩组成。该课程对学生的学习兴趣、实验技能、理论水平和文献查阅能力、团队合作精神及人际关系均有明显提高。学期末我们对该课程进行问卷调查, 得到学生的正面反馈, 学院教学督导委员会也对本课程的开设给予了充分的肯定。本课程对培养学生的创新能力及综合素质具有重要作用, 可以帮助学生理解每个二级学科的特点, 构建科学合理的知识体系, 增强对药物研发过程的整体理解。

关键词: 药学综合性实验, 本科生, 多学科, 药学, 实验教学

Abstract:

Pharmaceutical comprehensive study (PCS) is a new system of experimental teaching in China, which integrates multidisciplinary pharmaceutical knowledge and covers the basic process of new drug discovery. To explore the feasibility of this experiment teaching system and mode, we developed PCS as an elective course. The PCS is designed with two sections: pharmaceutical comprehensive design (PCD) and pharmaceutical comprehensive experiment (PCE). The PCD section includes literature review, comprehensive project design and oral examination. PCE can be divided into four parts: synthesis, quantitative determination, pharmacodynamic evaluation, and formulation and quality determination. Course grade was determined by experimental performance, written report, literature review, new project design and oral examination. The learning interest, experimental ability, theoretical level and literature retrieval ability, team spirit and interpersonal skills have been all significantly improved among students taking this course. A survey was administered at the end of the semester to the enrolled students. The responses were reported as percentages, and the feedback was positive. The course was highly recommended by the teaching inspection committee. This new course plays an important role in developing students’ creativity and comprehensive ability. It could help students understand the focus and features of every secondary discipline, as well as establish scientific and reasonable knowledge system. Most students can better understand the process of drug research after this course.

Key words: Pharmaceutical comprehensive experiment, Undergraduate, Multidisciplinary, Pharmaceutical sciences, Experiment teaching

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