Phytochemical screening and wound healing potential of Cuscuta reflexa

doi:10.5246/jcps.2015.05.038

中国药学(英文版) ›› 2015, Vol. 24 ›› Issue (5): 292-302.DOI: 10.5246/jcps.2015.05.038

Phytochemical screening and wound healing potential of Cuscuta reflexa

Tapsya Gautam¹, Surya Prakash Gautam², Raj K. Keservani^3*, Anil Kumar Sharma⁴

1. School of Pharmaceutical Sciences, Shoolini University, Solan 173212, India
2. Department of Pharmaceutics, CT Institute of Pharmaceutical Sciences, Sahapur, Jalandhar 144020, India
3. School of Pharmaceutical Sciences, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal 462036, India
4. Department of Pharmaceutics, Delhi Institute of Pharmaceutical Sciences and Research, New Delhi 110017, India

收稿日期:2015-02-14 修回日期:2015-03-25 出版日期:2015-05-20 发布日期:2015-03-29
通讯作者: Tel.: +917897803904

Phytochemical screening and wound healing potential of Cuscuta reflexa

Tapsya Gautam¹, Surya Prakash Gautam², Raj K. Keservani^3*, Anil Kumar Sharma⁴

1. School of Pharmaceutical Sciences, Shoolini University, Solan 173212, India
2. Department of Pharmaceutics, CT Institute of Pharmaceutical Sciences, Sahapur, Jalandhar 144020, India
3. School of Pharmaceutical Sciences, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal 462036, India
4. Department of Pharmaceutics, Delhi Institute of Pharmaceutical Sciences and Research, New Delhi 110017, India

Received:2015-02-14 Revised:2015-03-25 Online:2015-05-20 Published:2015-03-29
Contact: Tel.: +917897803904

摘要/Abstract

摘要：

The present study was to investigate pharmacognostical, phytochemical and pharmacological properties of extracts from stem of Cuscuta reflexa Roxb.Standard procedures have been followed to evaluate the pharmacognostical properties and preliminary screening of phytochemicals of Cuscuta reflexa Roxb. Albino Wistar rats (either sex) weighing 150–200 g were taken and made to acclimatize by providing them with the appropriate room conditions in the experimental room. Excision wound model has been selected for analgesic and wound healing activity for evaluating potential of the water-extract and ethanolicextract from the stem of Cuscuta reflexa Roxb. The macroscopic and microscopic studies showed the various characteristic features of stems. Preliminary screening of phytochemicals reveled that alkaloids, glycosides, flavonoids were the major groups of phytochemicals present in the successive extracts. Water and ethanolic extracts from stem of Cuscuta reflexa Roxb at 200 mg/kg and 400 mg/kg were able to alleviate pain and wounds. It is concluded that the stems of Cuscuta reflexa Roxb have a markedly therapeutic potential to heal wound and may provide the pharmacological basis for its folk uses.

关键词: Pharmacognostical, Phytochemical, Soframycin, Analgesic, Wound healing, Stem, Cuscuta reflexa Roxb

Abstract:

Key words: Pharmacognostical, Phytochemical, Soframycin, Analgesic, Wound healing, Stem, Cuscuta reflexa Roxb

中图分类号:

R284

Supporting:

Tapsya Gautam, Surya Prakash Gautam, Raj K. Keservani, Anil Kumar Sharma. Phytochemical screening and wound healing potential of Cuscuta reflexa[J]. 中国药学(英文版), 2015, 24(5): 292-302.

Tapsya Gautam, Surya Prakash Gautam, Raj K. Keservani, Anil Kumar Sharma. Phytochemical screening and wound healing potential of Cuscuta reflexa[J]. Journal of Chinese Pharmaceutical Sciences, 2015, 24(5): 292-302.

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Phytochemical screening and wound healing potential of Cuscuta reflexa

Phytochemical screening and wound healing potential of Cuscuta reflexa

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