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中国药学(英文版) ›› 2026, Vol. 35 ›› Issue (3): 328-328.

• 【新闻】 • 上一篇    

汤新景和杨振军团队合作开展基于pre-let-7的PROTAC分子靶向降解Lin28B蛋白用于肝癌治疗

北京大学药学院天然药物及仿生药物全国重点实验室   

  1. 北京大学药学院天然药物及仿生药物全国重点实验室
  • 收稿日期:2026-02-15 修回日期:2026-02-15 接受日期:2026-02-15 出版日期:2026-04-04 发布日期:2026-04-03

The research teams of Prof. Xinjing Tang and Prof. Zhenjun Yang collaborated on the targeted degradation of Lin28B using Pre-let-7-PROTACs for hepatocellular carcinoma therapy

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center   

  1. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center
  • Received:2026-02-15 Revised:2026-02-15 Accepted:2026-02-15 Online:2026-04-04 Published:2026-04-03

摘要:

2026年2月8日, 北京大学药学院天然药物及仿生药物全国重点实验室汤新景和杨振军研究团队在学术期刊Journal of Medicinal Chemistry上发表了最新研究成果“Targeted Degradation of Lin28B Using Pre-let-7-PROTACs for Hepatocellular Carcinoma Therapy”。

Abstract: The research teams of Prof. Xinjing Tang and Prof. Zhenjun Yang collaborated on the targeted degradation of Lin28B using 

Pre-let-7-PROTACs for hepatocellular carcinoma therapy.

Supporting: