摘要：
近日, 北京大学药学院天然药物及仿生药物全国重点实验室张力勤/张庆英/张友波团队合作, 在国际学术期刊Pharmacological Research上发表了题为“Cross-Kingdom Delivery and Putative Gene Modulation of Androgen Pathways by Plant-Derived Exosome-like Nanoparticles from Polygoni Multiflori Radix Promotes Hair Growth via miRNA Cargo”的研究论文, 首次揭示了何首乌中提取的植物外泌体样纳米颗粒能够通过递送植物源微小RNA, 跨物种调控人类毛囊细胞中的雄激素受体通路, 从而有效促进毛发生长、抑制雄激素性脱发。该研究为中药现代化及RNA纳米药物治疗脱发提供了全新视角。
Supporting:
北京大学药学院天然药物及仿生药物全国重点实验室. 张力勤/张庆英/张友波团队合作揭示中药何首乌跨物种基因调控新机制[J]. 中国药学(英文版), 2026, 35(1): 101-103.
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center. The team of Prof. Liqin Zhang, Prof. Qingying Zhang and Prof. Youbo Zhang has jointly revealed a new mechanism of cross-species gene regulation in the traditional Chinese medicine Polygonum multiflorum[J]. Journal of Chinese Pharmaceutical Sciences, 2026, 35(1): 101-103.
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