不同输液包装对药液残留量和输液治疗的经济性和有效性的影响

不同输液包装对药液残留量和输液治疗的经济性和有效性的影响

周欣, 陈利华, 翟所迪^*

北京大学第三医院药剂科, 北京 100191

收稿日期:2009-11-30 修回日期:2010-02-20 出版日期:2010-03-15 发布日期:2010-03-15
通讯作者: 翟所迪*

Influence of different intravenous injection containers on residual liquid volume and its economic impact

Xin Zhou, Li-Hua Chen, Suo-Di Zhai^*

Department of Pharmacy, Peking University Third Hospital, Beijing 100191, China

Received:2009-11-30 Revised:2010-02-20 Online:2010-03-15 Published:2010-03-15
Contact: Suo-Di Zhai*

摘要/Abstract

摘要： 本研究的目的在于考察临床实际应用过程中不同输液包装对药液残留量的影响; 通过收集2007年9~10月北京大学第三医院外科住院患者输液治疗后的0.9%氯化钠注射液包装 (5个品种, 共有100 mL、250 mL和500 mL 3种规格), 测定其中的药液残留量, 并根据患者用药资料进行相关的药物经济学分析。结果表明, 各个包装平均残留液量在0.38~4.8 mL的范围内, 残留量随原注射液容积增大而增多; 其中一种双阀软袋包装的残留量显著低于其它包装 (P<0.05), 而单阀软袋的残留量相对较高; 根据用药资料推算出的残留液相关药费在每年1.5~15万美元之间。可见不同输液包装对药液残留量的多少有显著影响, 选择适当的输液包装有利于提高输液治疗的经济性和有效性。

关键词: 输液包装, 药液残留, 经济性, 有效性

Abstract:

The objective of this study was to evaluate the influence of infusion container design on the volume of residual drug solution following use in a clinical setting. 0.9% (w/v) NaCl infusion solution containers (5 types, each of three capacities: 100 mL, 250 mL and 500 mL) following clinical use for in-patients at Peking University Third Hospital were collected during Sept. and Oct. 2007. The volume of residual drug solution was determined. Hospital pharmacy records were used to determine the potential economic implications of discarding residual drug solutions. The mean residual volumes ranged from 0.38 mL to 4.80 mL and, in general, residual volume increased with increasing container capacity. The residual volumes for one type of double-port soft bag were significantly lower than the residual volumes for all other containers of the same capacity (P<0.05), including glass and semi-rigid plastic bottles. Highest residual volumes were observed for the single-port soft bag. Estimates of the value of discarded residual drug solution ranged from approximately US $15,000 to US $150,000 per annum in our hospital. Infusion container design has a major influence on residual drug solution volumes following intravenous infusion. Appropriate choice of bag design remains an important consideration for the economics and efficacy of infusion treatment in Chinese hospitals.

Key words: Intravenous infusion containers, Residual solution, Economics, Efficacy

中图分类号:

Supporting:

^*Corresponding author. Tel.: 86-10-82265740

周欣, 陈利华, 翟所迪^*. 不同输液包装对药液残留量和输液治疗的经济性和有效性的影响[J]. .

Xin Zhou, Li-Hua Chen, Suo-Di Zhai^*. Influence of different intravenous injection containers on residual liquid volume and its economic impact [J]. .

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