肥皂荚Gymnocladus chinensis Baill.中两个三萜皂苷的结构鉴定

肥皂荚Gymnocladus chinensis Baill.中两个三萜皂苷的结构鉴定

王刊, 付宏征^*

北京大学天然药物及仿生药物国家重点实验室, 北京 100191

收稿日期:2009-03-18 修回日期:2009-05-10 出版日期:2009-06-15 发布日期:2009-06-15
通讯作者: 付宏征*

Structural determination of two triterpenoid saponins from Gymnocladus chinensis Baill.

Kan Wang, Hong-Zheng Fu^*

State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China

Received:2009-03-18 Revised:2009-05-10 Online:2009-06-15 Published:2009-06-15
Contact: Hong-Zheng Fu*

摘要/Abstract

摘要： 从肥皂荚Gymnocladus chinensis Baill. 提取出两个三萜皂苷类化合物 (化合物I与II) , 其中化合物I为新化合物, 通过核磁方法, 鉴定其为2β,23-dihydroxy-acacic acid-3-O-α-L-arabinopyranosyl-21-O-{(6S)-2-E-2,6-dimethyl-6-O-[4-O-(6S)-2-E-2,6-dimethyl-6-O-β-D-glucopyranosyl-α-L-arabinopyranosyl-2,7-octadienoyl}-28-O-β-D-xylopyranosyl(1→3)-β-D-xylopyranosyl(1→4)-α-L-rhamnopyranosyl(1→2)-[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside。

关键词: 一维/二维核磁共振波谱技术, 三萜皂苷, 肥皂荚

Abstract: Two triterpenoid saponins (compound I and II) have been isolated from Gymnocladus chinensis Baill., and compound I was determined as a new compound. The structure of compound I was assigned as 2β,23-dihydroxy-acacic acid-3-O-α-L-arabinopyranosyl-21-O-{(6S)-2-E-2,6-dimethyl-6-O-[4-O-(6S)-2-E-2,6-dimethyl-6-O-β-D-glucopyranosyl-α-L-arabinopyranosyl-2,7-octadienoyl}-28-O-β-D-xylopyranosyl(1→3)-β-D-xylopyranosyl(1→4)-α-L-rhamnopyranosyl(1→2)-[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside by extensive MS and NMR studies.

Key words: 1D/2D NMR, 1D/2D NMR, Triterpenoid saponins, Triterpenoid saponins, Gymnocladus chinensis Baill., Gymnocladus chinensis Baill.

中图分类号:

R284.1

Supporting:

Foundation item: National Natural Science Foundation of China (Grant No. 30772639).

^*Corresponding author. Tel.: 86-10-82805212; fax: 86-10-82802724;

e-mail: drhzfu@yahoo.com.cn

王刊, 付宏征^*. 肥皂荚Gymnocladus chinensis Baill.中两个三萜皂苷的结构鉴定[J]. .

Kan Wang, Hong-Zheng Fu^*. Structural determination of two triterpenoid saponins from Gymnocladus chinensis Baill. [J]. .

[1]	吴琼, 涂光忠, 付宏征. 九子参中一个新三萜皂苷[J]. 中国药学(英文版), 2014, 23(4): 246-250.
[2]	周渊, 李宁, 张加余, 姜勇, 屠鹏飞. RP-HPLC-DAD法同时测定毛冬青根中4种三萜皂苷和2种木脂素的含量[J]. 中国药学(英文版), 2014, 23(12): 866-872.
[3]	王超, 李军, 屠鹏飞. 岗梅叶的化学成分研究[J]. 中国药学(英文版), 2014, 23(11): 778-782.
[4]	宋丽军, 谭晓梅, 赵文昌, 罗佳波^*. HPLC-DAD法同时定量分析葛根芩连微丸中12种活性成分[J]. , 2010, 19(6): 464-470.
[5]	郭杰, 杨秀伟^*. 浙江七叶树种子中三萜皂苷成分的研究[J]. , 2004, 13(2): 87-91.
[6]	张建业, 杨秀伟^*. 罗汉果皂苷IVa碳氢NMR信号的归属[J]. , 2003, 12(4): 196-200.