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Chemical ingredients isolated from the aerial parts of Artemisia anomala

Ke Zan, Xiao-Qing Chen, Qiang Fu, Si-Xiang Zhou, Mei-Tian Xiao, Jing Wen, Peng-Fei Tu*   

  1. 1. School of Traditional Chinese Medicine, China Pharmaceutical University, Nanjing 210009, China
    2. State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing 100191, China
    3. Department of Chemical and Pharmaceutical Engineering, Huaqiao University, Quanzhou 362021, China
  • Received:2009-12-03 Revised:2010-02-10 Online:2010-03-15 Published:2010-03-15
  • Contact: Peng-Fei Tu*

Abstract:

Fourteen known compounds were isolated from the aerial parts of Artemisia anomala and identified as follows: zhepiresinol (1), (-)-lariciresinol (2), ficusal (3), medioresinol (4), (+)-syringaresinol (5), 1β,2β-epoxy-3β,4α,10α-trihydroxyguaian-6α,12-olide (6), 5β,10α-dihydroxy-1αH-dehydroleucodin (7), 3α-chloro-8α-acetoxy-4β,10α-dihydroxy-1β,2β-epoxy-5α,7αH-guai-11(13)-en-12,6α-olide (8), 13-O-desacetyleudesma-afraglaucolide (9), 1,10-seco-4ξ-hydroxy-muurol-5-ene-1,10-diketone (10), 1α-hydroxyafraglaucolide (11), aurantiamide (12), indole-3-aldehyde (13), loliolide (14). All these compounds were isolated from this plant for the first time and compounds 14, 8, 10, 13 were obtained from genus Artemisia for the first time.

Key words: Artemisia anomala, Compositae, Chemical constituents, Lignans, Sesquiterpenoids

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