High performance liquid chromatography for the determination of flavonoids

doi:10.5246/jcps.2011.04.039

Abstract

Abstract: Due to their biological and physiological importance, flavonoids receive considerable attention in the literature. Nowadays, high performance liquid chromatography (HPLC) is the most widely used analytical method. In this review, we summarize the principle of the choice of HPLC column and mobile phase, discuss and compare the features of various detections such as UV, fluorescence detection, electrochemical detection, chemiluminescence detection, UV-MS etc. Recent developments in HPLC including ultra-LC and miniaturization of LC (micro-LC, capillary-LC, and nano-LC), are also discussed.

Key words: High performance liquid chromatography, Flavonoids, Determination, Detection

CLC Number:

R284.1

Supporting:

Ming-Lei Chen, Wei Hu, Chao Zhang, Yun Fang^*. High performance liquid chromatography for the determination of flavonoids[J]. , DOI: 10.5246/jcps.2011.04.039.

References

[1] Kesarkar, S.; Bhandage, A.; Deshmukh, S.; Shevkar, K.; Abhyankar, M. J. Pharm. Res. 2009, 2, 1148-1154.
[2] Rijke, E.D.; Out, P.; Niessen, W.M.A.; Ariese, F.; Gooijer, C.; Brinkman, U.A.Th. J. Chromatogr. A. 2006, 1112, 31-63.
[3] Zhang, Y.Y.; Li, Z.C.; Zhu, J.K.; Yang, Z.Y.; Wang, Q.J.; He, P.G.; Fang, Y.Z.; Jin, K.Z.; Zhi, Y.Y.; Qing, J.W.; Pin, G.H.; Yu, Z.F. Chin. Chem. Lett. 2010, 21, 1231-1234.
[4] Ying, S.; Ning, F.; Chen, D.D.Y.; Donkor, K.K. Food Chem. 2008, 106, 415-420.
[5] Zehrmann, N.; Zidorn, C.; Ganzera, M. J. Pharm. Biomed. Anal. 2010, 51, 1165-1168.
[6] Ganzera, M.; Egger, C.; Zidorn, C.; Stuppner, H. Anal. Chim. Acta. 2008, 614, 196-200.
[7] Sutthanut, K.; Sripaanidkulchai, B.; Yenjai, C.; Jay, M. J. Chromatogr. A. 2007, 1143, 227-233.
[8] Füzfai, Z.; Molnάr-Perl, I. J. Chromatogr. A. 2007, 1149, 88-101.
[9] Canini, A.; Alesiani, D.; D’Arcangelo, G.; Tagliatesta, P. J. Food Comp. 2007, 20, 584-590.
[10] MaleŠ, Ž.; Medić-Šarić, M. J. Pharm. Biomed. Anal. 2001, 24, 353-359.
[11] Wang, Y.; He, J.M.; Chen, H.; Zhang, D.S.; Cai, H.; Shao, H.B. Chin. J. Anal. Chem. 2006, 34, 1073-1077.
[12] Molnάr-Perl, I.; Füzfai, Z. J. Chromatogr. A. 2005, 1073, 201-227.
[13] Vukics, V.; Guttman, A. Mass Spectrom. Rev. 2010, 29, 1-16.
[14] Vall, J.; Millán, S.; Martí, M.P.; Borràs, E.; Arola, L. J. Chromatogr. A. 2009, 1216, 7143-7172.
[15] Avula, B.; Wang, Y.H.; Smillie, T.; Fu, X.; Li, X.C.; Mabusela, W.; Syce, J.; Johnson, Q.; Folk, W.; Kan, A.I. J. Pharm. Biomed. Anal. 2010, 52, 173-180.
[16] Chen, X.J.; Guo, B.L.; Li, S.P.; Zhang, Q.W.; Tu, P.F.; Wang, Y.T. J. Chromatogr. A. 2007, 1163, 96-104.
[17] Repollés, C.; Herrero-Martínez, J.M.; Ràfols, C. J. Chromatogr. A. 2006, 1131, 51-57.
[18] Arapitsas, P.; Turner, C. Talanta. 2008, 74, 1218-1223.
[19] Zhang, H.; Guo, Z.M.; Zhang F.F.; Liang X.M. J. Sep. Sci. 2008, 31, 1623-1627.
[20] Maruška, A.; Kornyšova, O. J. Chromatogr. A. 2006, 1112, 319-330.
[21] Jandera, P. Anal. Chim. Acta. 2011, 692, 1-25.
[22] Van Nuijs, A.L.N.; Taromnicu, I.; Covaci, A. J. Chromatogr. A. doi:10.1016/j.chroma.2011.01.075
[23] Liu, R.X.; Sun, J.B.; Bi, K.S.; Guo, D.A. J. Chromatogr. A. 2005, 829, 35-44.
[24] Su, J.; Fu, P.; Shen, Y.H.; Zhang, C.; Liang, M.J.; Liu, R.H.; Li, H.L.; Zhang, W.D. J. Pharm. Biomed. Anal. 2008, 46, 342-348.
[25] Kostiainen, R.; Kauppila, T. J. Chromatogr. A. 2009, 1216, 685-699.
[26] Olszewska, M.A.; Gudej, J. J. Pharm. Biomed. Anal. 2009, 50, 771-777.
[27] Horvath, R.C.; Martos, A.P.; Saxena, K.P. J. Chromatogr. A. 2005, 1062, 199-207.
[28] Loon, Y.H.; Wong, J.W.; Yap, S.P.; Yuen, K.H. J. Chromatogr. B. 2005, 816, 161-166.
[29] Lu, Y.H.; Liu, Z.Y.; Wang, Z.T.; Wei, D.Z. J. Pharm. Biomed. Anal. 2006, 41, 1186-1190.
[30] Liu, R.X.; Sun, J.H.; Bi, K.S.; Guo, D.A. J. Chromatogr. B. 2005, 829, 35-44.
[31] Britton, G.R.; Fong, I.; Saad, S.; Brown, K.; Steward, P.W. J. Chromatogr. B. 2009, 877, 939-942.
[32] Paulke, A.; Schubert-Zsilavecz, M.; Wurglics, M. J. Chromatogr. B. 2006, 832, 109-113.
[33] Novak, I.; Janeiro, P.; Seruga, M.; Oliveira-Brett, A.M. Anal. Chim. Acta. 2008, 630, 107-115.
[34] Matsumoto, D.; Kotani, A.; Hakamata, H.; Takahashi, K.; Kusu, F. J. Chromatogr. A. 2010, 1217, 2986-2989.
[35] Gάmiz-Gracia, L.; García-Campaňa, M.A.; Huertas-Pérez, F.J.; Lara, J.F. Anal. Chim. Acta. 2009, 640, 7-28.
[36] Zhang, Q.L.; Cui, H.; Myint, A.; Lian, M.; Liu, L.J. J. Chromatogr. A. 2005, 1095, 94-101.
[37] Zhang, Q.L.; Zhang, Y.J.; Zhang, Z.T.; Lu, Z.D. J. Chromatogr. B. 2009, 877, 3595-3600.
[38] Li, B.X.; Guo, L.L.; Xu, C.L.; Ma, L.M. Spect. Acta. 2008, 71, 892-897.
[39] Han, J.; Ye, M.; Xu, M.; Sun, J.H.; Wang, B.R.; Guo, D.A. J. Chromatogr. B. 2007, 848, 355-362.
[40] Rijke, E.D.; Zappey, H.; Ariese, F.; Gooijer, G.; Brinkman, A.U. J. Chromatogr. A. 2003, 984, 45-58.
[41] Portet, B.; Fabre, N.; Rozenberg, R.; Habib-Jiwan, J.L.; Moulis, C.; Quetin-Leclercq, J. J. Chromatogr. A. 2008, 1210, 45-54.
[42] Marchi, I.; Rudaz, S.; Veuthey, J.L. Talanta. 2009, 78, 1-18.
[43] GÓmez-Ariza, J.L.; García-Barrera, T.; Lorenzo, F. Anal. Chim. Acta. 2006, 570, 101-108.
[44] Becchi, M.; Fraisse, D. Mass Spectrum. 1989, 18, 122-130.
[45] Shu, P.; Hong, J.L.; Wu, G.; Yu, B.Y.; Qin, M.J. Chin. J. Nat. Med. 2010, 8, 202-207.
[46] Souza, M.L.; Cipriani, R.T.; Iacomini, M.; Gorin, A.J.P.; Sassaki, L.G. J. Pharm. Biomed. Anal. 2008, 47, 59-67.
[47] Liu, G.Z.; Ma, J.Y.; Chen, Y.Z.; Tian, Q.Q.; Shen, Y.; Wang, X.S.; Chen, B.; Yao, S.Z. J. Chromatogr. A. 2009, 1216, 4809-4814.
[48] Su, J.; Fu, P.; Shen, Y.H.; Zhang, C.; Liang, M.J.; Liu, R.H.; Li, H.L.; Zhang, W.D. J. Pharm. Biomed. Anal. 2008, 46, 342-348.
[49] Inbaraj, B.S.; Lu, H.; Kao, T.H.; Chen, B.H. J. Pharm. Biomed. Anal. 2010, 51, 549-556.
[50] Kao, T.H.; Huang, S.C.; Inbaraj, B.S.; Chen, B.H. Anal. Chim. Acta. 2008, 626, 200-211.
[51] Piccinelli, A.L.; Mesa, M.G.; Armenteros, D.M.; Alfonso, M.A.; Arevalo, A.C.; Campone, L.; Rastrelli, L. J. Agric. Food Chem. 2008, 56, 1574-1581.
[52] Ola, S.S.; Catia, G.; Marzia, I.; Francesco, V.F.; Afolabi, A.A.; Nadia, M. Food Chem. 2009, 115, 1568-1574.
[53] Dehkharghanian, M.; Adenier, H.; Vijayalakshmi, A.M. Food Chem. 2010, 121, 863-870.
[54] Wu, C.S.; Guo, B.L.; Sheng, Y.X.; Zhang, J.L. Chin. Chem. Lett. 2008, 19, 329-332.
[55] Qian, Z.M.; Lu, J.; Gao, Q.P.; Li, S.P. J. Chromatogr. A. 2009, 1216, 3825-3830.
[56] Truchado, P.; Ferreres, F.; Tomas-Barberan, F.A. J. Chromatogr. A. 2009, 1216, 7241-7248.
[57] Termentzi, A.; Kefalas, P.; Kokkalou, E. Food Chem. 2008, 106, 1234-1245.
[58] Zhou, D.Y.; Xing, R.; Xu, Q.; Xue, X.Y.; Zhang, F.F.; Liang, X.M. J. Pharm. Biomed. Anal. 2008, 46, 543-549.
[59] Aguirre-Hernández, E.; González-Trujano, M.E.; Martínez, A.L.; Moreno, J.; Kite, G.; Terrazas, T.; Soto-Hernández, M. J. Ethnopharmcol. 2010, 127, 91-97.
[60] Quirantes-Piné, R.; Funes, L.; Micol, V.; Segura-Carretero, A.; Fernández-Gutiérrez, A. J. Chromatogr. A. 2009, 1216, 5391-5397.
[61] Abad-García, B.; Berrueta, L.A.; Garmón-Lobato, S.; Gallo, B.; Vicente, F. J. Chromatogr. A. 2009, 1216, 5398-5415.
[62] Spácil, Z.; Nováková, L.; Solich, P. Food Chem. 2010, 123, 535-541.
[63] Zhang, W.J.; Xu, M.; Yu, C.Q.; Zhang, G.F.; Tang, X. J. Chromatogr. B. 2010, 878, 1837-1844.
[64] Ortega, N.; Romero, M.P.; Macià, A.; Reguant, J.; Anglès, N.; Morelló, J.R.; Motilva, M.J. J. Food Compos. Anal. 2010, 23, 298-305.
[65] Deng, X.Y.; Gao, G.H.; Zheng, S.N.; Li, F.M. J. Pharm. Biomed. Anal. 2008, 48, 562-567.
[66] Yang, Z.; Zhu, W.; Gao, S.; Xu, H.Y.; Wu, B.J.; Kulkarni, K.; Singh, R.; Tang, L.; Hu, M. J. Pharm. Biomed. Anal. 2010, 53, 81-89.
[67] Chen, X.J.; Ji, H.; Zhang, Q.W.; Tu, P.F.; Wang, Y.T.; Guo, B.L.; Li, S.P. J. Pharm. Biomed. Anal. 2008, 46, 226-235.
[68] Yang, X.; Wang, B.C.; Zhang, X.; Yang, S.P.; Li, W.; Tang, Q.; Singh, G.K. J. Pharm. Biomed. Anal. 2011, 54, 311-316.
[69] Gratacós-Cubarsí, M.; Ribas-Agustí, A.; García-Regueiro, J.A.; Castellari, M. Food Chem. 2010, 121, 257-263.
[70] Zhou, D.Y.; Zhang, X.L.; Xu, Q.; Xue, X.Y.; Zhang, F.F.; Liang, X.M. J. Pharm. Biomed. Anal. 2009, 50, 2-8.
[71] Ouyang, G.F; Zhao, W.N.; Alaee, M.; Pawliszyn, J. J. Chromatogr. A. 2007, 1138, 42-46.
[72] Gjelstad, A.; Andersen, T.M.; Rasmussen, K.E.; Pedersen-Bjergaard, S. J. Chromatogr. A. 2007, 1157, 38-45.
[73] Yang, C.L.; Guo, L.Y.; Liu, X.Y.; Zhang, H.X.; Liu, M.C. J. Chromatogr. A. 2007, 1164, 56-64.
[74] Legido-Quigley, C.; Smith, N.W.; Mallet, D. J. Chromatogr. A. 2002, 976, 11-18.
[75] Vukics, V.; Ringer, T.; Kery, A.; K. Bonn, G.; Guttman, A. J. Chromatogr. A. 2008, 1206, 11-20.
[76] Hughey, C.A.; Wilcox, B.; Minardi, C.S.; Takehara, C.W.; Sundararaman, M.; Were, M.L. J. Chromatogr. A. 2008, 1192, 259-265.
[77] Chen, J.; Song, Y.; Li, P. J. Chromatogr. A. 2007, 1157, 217-226.
[78] Si-Ahmed, K.; Tazerouti, F.; Badjah-Hadj-Ahmed, A.Y.; Aturki, Z.; D'Orazio, G.; Rocco, A.; Fanali, S. J. Chromatogr. A. 2010, 1217, 1175-1182.
[79] Coufal, P.; Čihάk, M.; Suchάnkovά, J.; Tesařovά, E.; Bosάkovά, Z.; Štulík, K. J. Chromatogr. A. 2002, 946, 99-106.