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Journal of Chinese Pharmaceutical Sciences ›› 2014, Vol. 23 ›› Issue (6): 347-360.DOI: 10.5246/jcps.2014.06.048

• Review • Previous Articles     Next Articles

Chemistry of the Chinese herbal medicine Puerariae Radix (Ge-Gen): A review

Wei Song, Yanjiao Li, Xue Qiao, Yi Qian, Min Ye*   

  1. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China 
  • Received:2014-04-06 Revised:2014-04-24 Online:2014-06-28 Published:2014-05-05
  • Contact: Tel.: 86-10-82802024
  • About author:Dr. Ye graduated from Beijing University of Chinese Medicine in 2000 and obtained his B.Sc and M.Sc degrees. In 2003, he obtained his Ph.D. degree in Pharmacognosy from School of Pharmaceutical Sciences, Peking University. During 2003–2007, he did postdoctoral research at Peking University Health Science Center, Louisiana State University, and Yale University School of Medicine. In December 2007, he joined the School of Pharmaceutical Sciences at Peking University as an Associate Professor in Pharmacognosy and currently as a Professor. His research interest is quality control and DMPK of Chinese herbal medicines, and biotransformation of natural products.
  • Supported by:
    National Natural Science Foundation of China (Grant No. 81222054), and the Program for New Century Excellent Talents in University from Chinese Ministry of Education (Grant No. NCET-11-0019).

Abstract: Puerariae Radix (Ge-Gen in Chinese) is a popular traditional Chinese herbal medicine derived from the dried roots of Pueraria lobata (Willd.) Ohwi or P. thomsonii Benth. It shows significant pharmacological activities in the treatment of cardiovascular diseases, hypertension, and diabetes. This review summarizes progress in the chemistry study of Pueraria species, mainly covering the classes of flavonoids, puerosides, coumarins, triterpenoids, and triterpene saponins. Qualitative and quantitative chemical analyses are also covered.

Key words: Pueraria lobata, Pueraria thomsonii, Puerariae Radix, Chemical constituents, Chemical analysis

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