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Journal of Chinese Pharmaceutical Sciences

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Chemical constituents from the flowers of Rhododendron molle G. Don

Xuan Wang, Yanwei Hu, Dan Yuan*, Hongzheng Fu*   

  1. 1. College of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang 110016, China
    2. State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing 100191, China
  • Received:2013-05-03 Revised:2013-05-27 Online:2014-02-15 Published:2014-01-25
  • Contact: Dan Yuan*, Hongzheng Fu*
  • About author:*Corresponding author. Tel./Fax: 86-10-82805212; E-mail: drhzfu@sina.com
  • Supported by:
    National Natural Science Foundation of China (Grant No. 81172943).

Abstract:

The aim of current study was to investigate the chemical constituents from the flowers of Rhododendron molleG. Don. The isolation and purification of components were achieved by a series of chromatography including silica gel, Sephadex LH-20, and reversed-phase HPLC. Their structures were identified based on 1D, 2D NMR, and mass spectral analysis. Fifteen known compounds were isolated and their structures were identified as 2E,4Z-abscisic acid (1), 2α-hydroxy-oleanolic acid (2), oleanic acid (3), asiatic acid (4), benzyl glucoside (5), dibutyl phthalate (6), β-sitosterol (7), vitexin (8), quercetin (9), steraric acid (10), rhodomollein I (11), rhodojaponin VI (12), rhodomollein XI (13), rhodojaponin II (14), kalmanol (15). Compounds 110 were isolated from Rhododendron molle for the first time.

Key words: Rhododendron molle, Chemical constituents, Structural identification

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