Assignment of the absolute stereochemistry of an unusual diterpenoid from the mangrove plant Excoecaria agallocha L.

Abstract

Abstract:

An unusual diterpenoid excoagallochaol A (1), together with epi-β-amyrin (2), epitaraxerol (3), epi-α-amyrin (4), epilupeol (5), betulin (6), betulinic acid (7), lupenone (8), betulone (9), betulonic acid (10), (9Z,12Z,15Z)-2,3-dihydroxypropyl octadecatrienoate (11), and (9Z,12Z)-2,3-dihydroxypropyl octadecadienoate (12)were isolated from the stems of Excoecaria agallocha L. Their structures were elucidated by spectroscopic analyses, and the absolute stereochemistry of 1 was assigned using Mosher method. Compounds 4, 8, 10-12 were isolated from the genus Excoecaria for the first time.

Key words: Excoecaria agallocha, Mangrove plant, Chemical constituents

CLC Number:

R284.1

Supporting:

Zhen Liu, Wei Jiang, Zhi-Wei Deng, Wen-Han Lin^* . Assignment of the absolute stereochemistry of an unusual diterpenoid from the mangrove plant Excoecaria agallocha L. [J]. .

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Assignment of the absolute stereochemistry of an unusual diterpenoid from the mangrove plant Excoecaria agallocha L.

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