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Chemical constituents from Xylosma controversum

Zheng-Ren Xu, Ya-Nan Lu, Xing-Yun Chai, Hong-Yan Ren, Peng-Fei Tu*   

  1. School of Pharmaceutical Sciences, Peking University, Beijing 100083, China
  • Received:2006-11-16 Revised:2007-08-10 Online:2007-09-15 Published:2007-09-15
  • Contact: Peng-Fei Tu*

Abstract: Aim To study the chemical constituents from the stems of Xylosma controversum Clos. Methods The constituents were isolated by solvent extraction, repeated chromatography with silica gel, Sephadex LH-20, and RP-18 columns. The structures were elucidated by spectral analysis. Results Thirteen compounds were isolated and their structures were identified as (-)-syringaresinol (1), syringaresinol-4-O-β-D-glucopyranoside (2), syringaresinol-4,4'-bis-O-β-D-glucopyranoside (3), (±)-catechin (4), catechin-3-O-β-D-glucopyranoside (5), catechin-5-O-β-D-glucopyranoside (6), 1,3-bis-(4-hydroxy-3,5-dimethoxyphenyl)-1,3-propanediol (7), (R)-(+)-chaulmoogric acid (8), friedelin (9), uracile (10), benzoic acid (11), vanillic acid (12), and 4-hydroxybenzoic acid (13). Conclusion All the compounds described above were isolated from this genus for the first time.

Key words: Flacourtiaceae, Flacourtiaceae, Xylosma controversum, Xylosma controversum, Chemical constituents, Chemical constituents

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