Abstract: A simple, rapid and versatile capillary zone electrophoresis method was developed for the determination of chlorogenic acid as a marker in traditional Chinese medicines. The buffer solution used was a solution consisting of 10 mmol·L^-1 phosphate and 20 mmol·L^-1 boric acid containing 5% ethanol with the apparent pH value adjusted to 7.00. The linear calibration range was 27.7~65 μg·mL^-1 (r = 0.9996). The contents of chlorogenic acid in Flos Lonicerae and eight Flos Lonicerae containing Chinese medicines wee easily determined within 15 min with the sameprocedure.

Key words: Capillary electrophyoresis, Flos Lonicerae, Chlorogenic acid, Traditional Chinese medicine, Quantitation