Triterpenoids from the stems of Casearia velutina Bl.

doi:10.5246/jcps.2012.03.036

Abstract

Abstract:

To investigate the chemical components from the stems of Casearia velutina Bl., the constituents were isolated by repeated chromatography with silica gel, Sephadex LH-20, and ODS columns. The structures were elucidated by spectroscopic analysis. Eleven triterpenoids and its glycosides were isolated from the crude extract of C. velutina, and their structures were identified as friedelin-2,3-lactone (1), friedelane (2), epifriedelanol (3), friedelin (4), 2α,3α,19α-trihydroxy-urs-12-en-28-oic acid (5), 2α,3β,19α-trihydroxy-urs-12-en-28-oic acid (6), 2α,3α,23-trihydroxy-urs-12-en-28-oic acid (7), 2α,3α,23-trihydroxy-olean-12-en-28-oic acid (8), 2α,3α,19α,23-tetrahydroxy-urs-12-en-28-oic acid (9), 2α,3α,19α,23-tetrahydroxy-urs-12-en-28-oic acid-28-O-β-D-glucopyranosyl ester (10), and 3β,19α-dihydroxy-urs-12-en-28-oic acid 3-O-α-L-arabinopyranoside (11). All the compounds described above were isolated from this species for the first time. Compound 1 is a rarely occurred seco-friedelolactone in Flacourtiaceae.

Key words: Casearia velutina Bl., Flacourtiaceae, Triterpenoid, Chemical constituents

CLC Number:

R284.1

Supporting:

Fei-Fei Li, Zhi-Qin Guo, Xing-Yun Chai, Peng-Fei Tu^*. Triterpenoids from the stems of Casearia velutina Bl.[J]. , DOI: 10.5246/jcps.2012.03.036.

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