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中国药学(英文版) ›› 2026, Vol. 35 ›› Issue (4): 404-404.

• 【新闻】 • 上一篇    

王坚成团队开发了一种DC样巨噬细胞来源的纳米囊泡用于增强肿瘤免疫治疗

北京大学药学院天然药物及仿生药物全国重点实验室   

  1. 北京大学药学院天然药物及仿生药物全国重点实验室
  • 收稿日期:2026-03-05 修回日期:2026-03-05 接受日期:2026-03-05 出版日期:2026-05-05 发布日期:2026-05-07

The research team of Prof. Jiancheng Wang developed a type of nanovesicles derived from engineered DC-like M1 macrophage for enhancing tumor immunotherapy

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center   

  1. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center
  • Received:2026-03-05 Revised:2026-03-05 Accepted:2026-03-05 Online:2026-05-05 Published:2026-05-07

摘要:

近日, 北京大学药学院天然药物及仿生药物全国重点实验室王坚成教授团队在药学领域顶尖期刊Acta Pharmaceutica Sinica B在线发表了题为“Enhanced tumor immunotherapy by nanovesicles derived from engineered DC-like M1 macrophage”的研究论文。该研究开发了一种具有免疫调节功能的工程化纳米囊泡MAC-PNV, 通过同时激活CD8⁺T细胞和重塑免疫抑制肿瘤微环境, 实现了显著的抗肿瘤效果, 并为化疗药物联用治疗提供了新的增效减毒策略。

Abstract:

The research team of Prof. Jiancheng Wang developed a type of nanovesicles derived from engineered DC-like M1 macrophage for enhancing tumor immunotherapy.

Supporting: