曾克武/屠鹏飞揭示天然分子芦荟素自组装体靶向调控神经免疫炎症的新机制

中国药学(英文版) ›› 2025, Vol. 34 ›› Issue (11): 1058-1058.

曾克武/屠鹏飞揭示天然分子芦荟素自组装体靶向调控神经免疫炎症的新机制

北京大学药学院天然药物及仿生药物全国重点实验室

北京大学药学院天然药物及仿生药物全国重点实验室

收稿日期:2025-11-03 修回日期:2025-11-03 接受日期:2025-11-03 出版日期:2025-12-02 发布日期:2025-12-02

The research group of Prof. Kewu Zeng and Prof. Pengfei Tu revealed new mechanism of targeted regulation of neuroimmune inflammation by Aloin NPs

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center

Received:2025-11-03 Revised:2025-11-03 Accepted:2025-11-03 Online:2025-12-02 Published:2025-12-02

摘要/Abstract

摘要：

近日, 北京大学药学院天然药物及仿生药物全国重点实验室曾克武研究员与屠鹏飞教授在国际学术期刊ACS Nano上合作发表了题为“Nanoparticles Induce Protein Corona Conformational Change to Reshape Intracellular Interactome for Microglial Polarization”的研究论文, 深入阐明了芦荟活性成分芦荟素自组装体(Aloin NPs)调控神经小胶质细胞介导免疫炎症进而改善神经退行性疾病的全新分子靶点及作用机制。

Supporting:

北京大学药学院天然药物及仿生药物全国重点实验室. 曾克武/屠鹏飞揭示天然分子芦荟素自组装体靶向调控神经免疫炎症的新机制[J]. 中国药学(英文版), 2025, 34(11): 1058-1058.

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center. The research group of Prof. Kewu Zeng and Prof. Pengfei Tu revealed new mechanism of targeted regulation of neuroimmune inflammation by Aloin NPs[J]. Journal of Chinese Pharmaceutical Sciences, 2025, 34(11): 1058-1058.