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中国药学(英文版) ›› 2023, Vol. 32 ›› Issue (10): 863-864.

• 【新闻】 • 上一篇    

叶敏/乔雪团队在黄芪皂苷酰基转移酶的催化机制及理性改造中取得新进展

北京大学药学院 天然药物及仿生药物全国重点实验室   

  1. 北京大学药学院 天然药物及仿生药物全国重点实验室
  • 收稿日期:2023-10-09 修回日期:2023-10-09 接受日期:2023-10-09 出版日期:2023-11-04 发布日期:2023-11-06

The team of Prof. Min Ye and Prof. Xue Qiao have made new progress in the catalytic mechanism and rational transformation of regiospecific saponin acetyltransferase from Astragalus membranaceus

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center   

  1. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center
  • Received:2023-10-09 Revised:2023-10-09 Accepted:2023-10-09 Online:2023-11-04 Published:2023-11-06

摘要:

2023年9月25日, 北京大学药学院院天然药物及仿生药物全国重点实验室叶敏/乔雪研究团队在国际著名期刊Nature Communications上在线发表研究论文“Characterization and structure-based protein engineering of a regiospecific saponin acetyltransferase from Astragalus membranaceus”, 进一步完善了黄芪皂苷生物合成的下游途径。

Abstract:

The team of Prof. Min Ye and Prof. Xue Qiao have made new progress in the catalytic mechanism and rational transformation of regiospecific saponin acetyltransferase from Astragalus membranaceus.

Supporting: