中药传统鉴定技术的传承与本草文化推广

doi:10.5246/jcps.2020.12.080

中国药学(英文版) ›› 2020, Vol. 29 ›› Issue (12): 908-914.DOI: 10.5246/jcps.2020.12.080

中药传统鉴定技术的传承与本草文化推广

赵中振¹^,²^,^*(), 陈虎彪¹, 郭平¹, 梁之桃¹, 白效龙¹^,², 黄丽丽¹, 刘靖¹

1. 香港浸会大学中医药学院, 香港 999077
2. 北京中医药大学中药学院, 北京 102488

收稿日期:2020-09-15 修回日期:2020-09-26 接受日期:2020-10-18 出版日期:2020-12-30 发布日期:2020-12-30
通讯作者: 赵中振
作者简介:
+ Tel.: +852-34112424; Fax: +852-34112461, E-mail: zzzhao@hkbu.edu.hk
基金资助:
Research Grants Council (Grant No. 12103919) of Hong Kong.

Integrating ancient and modern approaches to traditional Chinese medicinal authentication

Zhongzhen Zhao¹^,²^,^*(), Hubiao Chen¹, Ping Guo¹, Zhitao Liang¹, Eric Brand¹^,², Lailai Wong¹, Jing Liu¹

1 School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong 999077, China
2 School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China

Received:2020-09-15 Revised:2020-09-26 Accepted:2020-10-18 Online:2020-12-30 Published:2020-12-30
Contact: Zhongzhen Zhao

About author:

Prof. Zhongzhen Zhao, Chair Professor of School of Chinese Medicine, Hong Kong Baptist University and Distinguished Professor of Beijing University of Traditional Chinese Medicine. Prof. Zhao also has served as the advisor of Traditional Medicines in the West Pacific Region of World Health Organisation and of the USP Dietary Supplements-Botanicals Expert Committee Member of Chinese Medicines Board, Chinese Medicine Council of Hong Kong and International Advisory Board, HK Standard of Chinese Materia Medica, Department of Health, HK and Chinese Pharmacopoeia Committee, China. He has been the Research Director of Laboratory of Chinese Medicine, ISKRA Industry Co. LTD, Japan from 1992 to 1999. Prof. Zhao was invited as Visiting Professor in Osher Research Center Harvard Medical School during his Sabbatical Leave (July 2009-January 2010). He was awarded the Medal of Honor by the Hong Kong Special Administrative Region Government in 2014.

摘要/Abstract

摘要：

中药鉴定是中药标准化和国际化的基础。中药的真伪优劣鉴定研究有着现代科学和传统文化的双重内涵, 不仅是长久以来尚未解决好的历史难题, 也是保障安全用药的前沿学术课题。中药鉴定牵涉到中药资源、中药性状鉴别、中药显微鉴别、本草文献研究等方面, 这些学科相互广联、相互配合。将传统鉴别经验用现代科学方法加以诠释具有紧迫的现实意义和长远的科学价值。本文通过结合中医药专著的编撰、中药标本中心的建设、中药数字化项目的创建、中药鉴定技术的拓展、《本草纲目》文化工程的推广, 探索中药鉴定学科及本草文化的传承之路。

关键词: 中药鉴定, 性状/显微鉴定, 本草, 本草文化工程

Abstract:

Authentication is a key component of quality control, and the quality of Chinese medicinal materials directly impacts clinical efficacy. Chinese medicinal quality control is an important concern of the wider community, and it is intricately connected to the future and development of Chinese medicine. Macroscopic identification has been used for thousands of years in Chinese medicine, and it continues to be effective for resolving important issues related to quality control in the modern-day. However, new challenges have emerged for macroscopic identification. For example, new botanical varieties have emerged, with differences in macroscopic features related to cultivated vs. wild materials. Changes in processing methods and cultivation techniques also affect these features. Consequently, continual progress and innovation in Chinese medicinal authentication methods are needed. Macroscopic identification is based on organoleptic assessment, microscopy, and research of ancient texts, such as the Bencao. In addition to collecting information from traditional experience-based differentiation, innovation can take advantage of new technologies that can provide even more detailed, precise information about morphology. In the present review, we summarized inheritance and innovation in the scientific exposition of Chinese medicinal authentication, featuring a review of specialized publications, description of the establishment of a Chinese medicine specimen center and Chinese Medicine digital project, the expansion of authentication technologies, and the formation of a cultural project dedicated to the Compendium of Materia Medica.

Key words: Chinese medicinal authentication, Macro-/microscopic identification, Bencao, Traditional Chinese medicinal cultural promotion

Supporting:

赵中振, 陈虎彪, 郭平, 梁之桃, 白效龙, 黄丽丽, 刘靖. 中药传统鉴定技术的传承与本草文化推广[J]. 中国药学(英文版), 2020, 29(12): 908-914.

Zhongzhen Zhao, Hubiao Chen, Ping Guo, Zhitao Liang, Eric Brand, Lailai Wong, Jing Liu. Integrating ancient and modern approaches to traditional Chinese medicinal authentication[J]. Journal of Chinese Pharmaceutical Sciences, 2020, 29(12): 908-914.

参考文献 17

[1]	Zhao, Z.Z.; Chen, H.B.; Guo, P.; Liang, Z.T.; Brand, E.; Wong, L.L. Establishment of Platforms to Facilitate the Inheritance and Innovation of Chinese Medicinal Authentication. J. Jpn. Bot. 2016, 91, 412–417.
[2]	Zhao, Z.Z.; Xiao, P.G. Encyclopedia of Medicinal Plants. Shanghai: Shanghai World Publishing. 2006.
[3]	Zhao, Z.Z.; Li, Y.S. Easily Confused Chinese Medicines in Hong Kong. Hong Kong: Chinese Medicine Merchants Association Ltd. 2007.
[4]	Zhao, Z.Z.; Chen, H.B. Chinese Medicinal Identification, An Illustrated Approach. Fujian: Fujian Science & Technology Publishing House. 2010.
[5]	Zhao, Z.Z.; Chen, H.B. Chinese Medicinal Microscopic Identification. Fujian: Fujian Science & Technology Publishing House. 2017.
[6]	Zhao, Z.Z.; Shimomura, H.; Sashida, Y.; Tujino, R.; Okamoto, T.; Kazami, T. Identification of traditional Chinese patent medicines by means of a polarizing microscope. (3) Polariscopic characteristics of Zhibao sanbian Wan. J. Nat. Med. 1998, 6, 485–490.
[7]	Liang, Z.T.; Jiang, Z.H.; Leung, K.S.Y.; Peng, Y.; Zhao, Z.Z. Distinguishing the medicinal herb Oldenlandia diffusa from similar species of the same genus using fluorescence microscopy. Microsc. Res. Tech. 2006, 69, 277–282.
[8]	Huang, X.; Liang, Z.; Chen, H.; Zhao, Z.; Li, P. Identification of Chinese herbal medicines by fluorescence microscopy: fluorescent characteristics of medicinal bark. J. Microsc. 2014, 256, 6–22.
[9]	Tong, C.S.; Choy, S.K.; Zhao, Z.Z.; Liang, Z.T.; Chen, H.B. Identification of starch grains in microscopic images based on granulometric operations. Microsc. Res. Tech. 2007, 70, 724–732.
[10]	Zhao, Z.Z.; Liang, Z.T.; Ping, G. Macroscopic identification of Chinese medicinal materials: traditional experiences and modern understanding. J. Ethnopharmacol. 2011, 134, 556–564.
[11]	Yi, L.; Liang, Z.T.; Peng, Y.; Yao, X.; Chen, H.B.; Zhao, Z.Z. Tissue-specific metabolite profiling of alkaloids in Sinomenii Caulis using laser microdissection and liquid chromatography–quadrupole/time of flight-mass spectrometry. J. Chromatogr. A. 2012, 1248, 93–103.
[12]	Ng, K.M.; Liang, Z.T.; Lu, W.; Tang, H.W.; Zhao, Z.Z.; Che, C.M.; Cheng, Y.C. In vivo analysis and spatial profiling of phytochemicals in herbal tissue by matrix-assisted laser desorption/ionization mass spectrometry. Anal. Chem. 2007, 79, 2745–2755.
[13]	Jaiswal, Y.; Liang, Z.T.; Ho, A.; Wong, L.; Yong, P.; Chen, H.B.; Zhao, Z.Z. Distribution of toxic alkaloids in tissues from three herbal medicine Aconitum species using laser micro-dissection, UHPLC-QTOF MS and LC-MS/MS techniques. Phytochemistry. 2014, 107, 155–174.
[14]	Yi, L.; Liang, Z.T.; Peng, Y.; Guo, P.; Wong, L.L.; Wan, X.J.; Ho, H.M.; Yi, T.; Zhao, Z.Z. Histochemical evaluation of alkaloids in rhizome of Coptis chinensis using laser microdissection and liquid chromatography/mass spectrometry. Drug Test. Anal. 2015, 7, 519–530.
[15]	Chen, Y.J.; Liang, Z.T.; Zhu, Y.; Xie, G.Y.; Tian, M.; Zhao, Z.Z.; Qin, M.J. Tissue-specific metabolites profiling and quantitative analyses of flavonoids in the rhizome of Belamcanda chinensis by combining laser-microdissection with UHPLC-Q/TOF-MS and UHPLC-QqQ-MS. Talanta. 2014, 130, 585–597.
[16]	Liang, Z.T.; Sham, T.; Yang, G.Y.; Yi, L.; Chen, H.B.; Zhao, Z.Z. Profiling of secondary metabolites in tissues from Rheum palmatum L. using laser microdissection and liquid chromatography mass spectrometry. Anal. Bioanal. Chem. 2013, 405, 4199–4212.
[17]	Liang, Z.T.; Oh, K.; Wang, Y.Q.; Yi, T.; Chen, H.B.; Zhao, Z.Z. Cell type-specific qualitative and quantitative analysis of saikosaponins in three Bupleurum species using laser microdissection and liquid chromatography–quadrupole/time of flight-mass spectrometry. J. Pharm. Biomed. Anal. 2014, 97, 157–165.

中药传统鉴定技术的传承与本草文化推广

Integrating ancient and modern approaches to traditional Chinese medicinal authentication

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