http://jcps.bjmu.edu.cn

中国药学(英文版) ›› 2026, Vol. 35 ›› Issue (2): 151-161.DOI: 10.5246/jcps.2026.02.011

• 【研究论文】 • 上一篇    下一篇

医疗机构钙通道阻滞剂类药品评价指标体系的构建

曹晶晶1, 王雷1, 赵成龙1, 钱雅婷2, 刘伟2,*()   

  1. 1. 河南省人民医院 药学部, 郑州大学人民医院, 河南 郑州 450003
    2. 郑州大学 药学院, 河南 郑州 450001
  • 收稿日期:2025-11-12 修回日期:2025-12-20 接受日期:2026-01-04 出版日期:2026-03-05 发布日期:2026-03-05
  • 通讯作者: 刘伟

Development of an evaluation index system for calcium channel blockers in healthcare institutions

Jingjing Cao1, Lei Wang1, Chenglong Zhao1, Yating Qian2, Wei Liu2,*()   

  1. 1. Department of Pharmacy, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, School of Clinical Medicine, Henan University, Zhengzhou 450003, Henan, China
    2. School of Pharmacy, Zhengzhou University, Zhengzhou 450001, Henan, China
  • Received:2025-11-12 Revised:2025-12-20 Accepted:2026-01-04 Online:2026-03-05 Published:2026-03-05
  • Contact: Wei Liu

摘要:

本研究旨在构建医疗机构钙通道阻滞剂 (CCB)类药品评价指标体系, 为医疗机构CCB类药品评价和遴选工作提供科学依据。参照《药品临床综合评价管理指南》 (2021年版试行), 并基于德尔菲法构建CCB类药品多准则、多维度的评价指标体系。结果发现, 经过两轮专家线上问卷咨询, 最终确定了以6个一级指标、23个二级指标、52个三级指标为核心的CCB类药品评价指标体系。两轮专家函询的熟悉程度分别为0.83、0.79, 判断依据系数分别为0.92、0.93, 权威系数分别为0.88、0.86; 信度分别为0.96、0.98。由此可得, 所构建的CCB类药品评价指标体系具有可推广性, 能够为医疗机构CCB类药品目录遴选及合理使用、提高药学服务、控制不合理药品费用支出等提供重要依据。

关键词: 钙通道阻滞剂, 药品评价, 德尔菲法

Abstract:

This study aimed to develop an evaluation index system for calcium channel blocker (CCB) drugs in medical institutions to support a scientific and evidence-based approach to their assessment and selection. In accordance with the Management Guidelines for Comprehensive Clinical Evaluation of Drugs (2021 Trial Edition) and utilizing the Delphi method, we established a comprehensive evaluation index system for CCB drugs. Two rounds of online expert consultations were conducted, resulting in a finalized system comprising six primary indicators, 23 secondary indicators, and 52 tertiary indicators. The average familiarity scores of experts were 0.83 and 0.79 across the two rounds, with judgment basis coefficients of 0.92 and 0.93, authority coefficients of 0.88 and 0.86, and credibility scores of 0.96 and 0.98, respectively. The developed evaluation index system exhibited robust credibility and wide applicability. It provided a structured framework to guide the selection and rational use of CCB drugs in medical institutions, thereby enhancing pharmacy service quality and facilitating optimized drug cost management.

Key words: Calcium channel blockers, Drug evaluation, Delphi method

Supporting: