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中国药学(英文版) ›› 2025, Vol. 34 ›› Issue (3): 293-298.

• 【新闻】 • 上一篇    

北京大学张力勤团队开发靶向蛋白质降解的核酸适体进化平台

北京大学药学院天然药物及仿生药物全国重点实验室   

  1. 北京大学药学院天然药物及仿生药物全国重点实验室
  • 收稿日期:2025-03-07 修回日期:2025-03-07 接受日期:2025-03-07 出版日期:2025-03-31 发布日期:2025-04-03

The research team of Prof. Liqin Zhang developed a functional oligonucleotides evolution platform targeting protein degradation

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center   

  1. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center
  • Received:2025-03-07 Revised:2025-03-07 Accepted:2025-03-07 Online:2025-03-31 Published:2025-04-03

摘要:

2025年2月5日, 北京大学药学院天然药物及仿生药物全国重点实验室张力勤研究员团队在Chem杂志上发表了题为“Systematic evolution of functional oligonucleotides for targeted protein degradation”的研究论文, 提出了一种基于核酸适体的系统性进化平台, 用于高效开发靶向蛋白质降解分子。

Abstract: The research team of Prof. Liqin Zhang developed a functional oligonucleotides evolution platform targeting protein degradation.

Supporting: