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中国药学(英文版) ›› 2025, Vol. 34 ›› Issue (12): 1147-1147.

• 【新闻】 • 上一篇    

董甦伟团队发展易聚集糖肽化学合成新策略

北京大学药学院天然药物及仿生药物全国重点实验室   

  1. 北京大学药学院天然药物及仿生药物全国重点实验室
  • 收稿日期:2025-11-20 修回日期:2025-11-20 接受日期:2025-11-20 出版日期:2025-12-31 发布日期:2025-12-31

The team of Prof. Suwei Dong has developed a new strategy for the chemical synthesis of aggregation-prone GlcNAcylated peptides

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center   

  1. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center
  • Received:2025-11-20 Revised:2025-11-20 Accepted:2025-11-20 Online:2025-12-31 Published:2025-12-31

摘要:

2025年10月30日, 学术期刊J. Am. Chem. Soc.在线刊登了北京大学药学院天然药物及仿生药物全国重点实验室董甦伟课题组最新研究成果“Traceless 6-O-Lysyl Modification of N-Acetylglucosamine Enables Synthesis and Derivatization of Aggregation-Prone GlcNAcylated Peptides”(通过N-乙酰葡糖胺的无痕6-O-赖氨酰修饰实现聚集倾向型GlcNAc修饰肽的合成与衍生)。

Abstract:

The team of Prof. Suwei Dong has developed a new strategy for the chemical synthesis of aggregation-prone GlcNAcylated peptides.

Supporting: