显齿蛇葡萄化学成分研究

显齿蛇葡萄化学成分研究

张岩松, 张庆英, 王邠, 李丽英, 赵玉英^*

1.北京大学医学部药学院天然药物学系, 北京 100083;
2.首都医科大学生物遗传学系, 北京 100054

收稿日期:2006-07-28 修回日期:2006-11-10 出版日期:2006-12-15 发布日期:2006-12-15
通讯作者: 赵玉英*

Chemical Constituents from Ampelopsis grossedentata

ZHANG Yan-song, ZHANG Qing-ying, WANG Bin, LI Li-ying, ZHAO Yu-ying^*

1.Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Centre, Beijing 100083, China;
2.Department of Cell Biology and Genetics, Capital University of Medical Sciences, Beijing 100054, China

Received:2006-07-28 Revised:2006-11-10 Online:2006-12-15 Published:2006-12-15
Contact: ZHAO Yu-ying*

摘要/Abstract

摘要： 目的研究显齿蛇葡萄的化学成分。方法应用硅胶、聚酰胺、反相硅胶、Sephadex LH-20柱色谱和硅胶制备薄层色谱进行分离纯化, 根据理化常数和光谱分析鉴定结构。结果从显齿蛇葡萄中分离并鉴定了4个黄酮类化合物: 二氢杨梅素(1), 杨梅素(2), 杨梅苷(3), 杨梅素-3-O-β-D-半乳糖苷(4)。结论其中化合物4为首次从该属植物中分离得到, 根据2D NMR正确归属了化合物1的¹H and ¹³C NMR数据。

关键词: 显齿蛇葡萄, 显齿蛇葡萄, 显齿蛇葡萄, 二氢杨梅素, 二氢杨梅素, 二氢杨梅素, 杨梅素, 杨梅素, 杨梅素, 杨梅苷, 杨梅苷, 杨梅苷, 杨梅素-3-O-β-D-半乳糖苷, 杨梅素-3-O-β-D-半乳糖苷, 杨梅素-3-O-β-D-半乳糖苷

Abstract: Aim To study chemical constituents from Ampelopsis grossedentata. Methods Separation and purification were performed by using silica gel, polyamide, reverse-phase silica gel, Sephadex LH-20 column chromatographic techniques and silica gel PTLC. Structures were determined by means of physicochemical properties and spectral analysis. Results Four flavonoids were separated and identified from Ampelopsis grossedentata including dihydromyricetin (1), myricetin (2), myricitrin (3), and myricetin-3-O-β-D-galactopyranoside (4). Conclusion Compound 4 was isolated from this genus for the first time, and 2D NMR techniques permitted the correct assignment of ¹H and ¹³C NMR signals of 1.

Key words: Ampelopsis grossedentata, Ampelopsis grossedentata, dihydromyricetin, dihydromyricetin, myricetin, myricetin, myricitrin, myricitrin, myricetin-3-O-β-D-galactopyranoside, myricetin-3-O-β-D-galactopyranoside

中图分类号:

R284.1

R284.2

Supporting: ^*Corresponding author. Tel.: 86-10-82801592

张岩松, 张庆英, 王邠, 李丽英, 赵玉英^*. 显齿蛇葡萄化学成分研究[J]. .

ZHANG Yan-song, ZHANG Qing-ying, WANG Bin, LI Li-ying, ZHAO Yu-ying^*. Chemical Constituents from Ampelopsis grossedentata[J]. .

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