YIGSK和含RGD多肽的抗血小板聚集作用

YIGSK和含RGD多肽的抗血小板聚集作用

迪丽努尔·莎比托夫, 赵明, 王超, 彭师奇^*

1. 北京医科大学中德联合实验室, 北京 100083;
2. 新疆维吾尔自治区药检所, 乌鲁木齐830002

收稿日期:1997-07-14 修回日期:1997-12-16 出版日期:1998-09-15 发布日期:1998-09-15
通讯作者: 彭师奇*

Antiplatelet Aggregation Effects of YIGSK and RGD Containing Peptides

Dilinur Shabitofu, Ming Zhao, Chao Wang, Shi-Qi Peng^*

1. School of Pharmaceutical Sciences, Beijing Medical University, Beijing 100083;
2. Xin Jiang Uygur Autonomous Regional Institute of Control for Pharmaceutical Products, Urumqi 830002

Received:1997-07-14 Revised:1997-12-16 Online:1998-09-15 Published:1998-09-15
Contact: Shi-Qi Peng*

摘要/Abstract

摘要： 观察了YIGSK, RGDS, RGDV, RGDF, YIGSKRGDS, YIGSKRGDV和YIGSKRGDF的抗血小板聚集作用, 通过比较它们的活性, 发现将YIGSK和含RGD多肽偶联可增强某些化合物的抗血小板聚集活性。

关键词: YIGSK, 含RGD多肽, 抗血小板聚集作用

Abstract: Antiplatelet aggregation effects of YIGSK, RGDS, RGDV, RGDF, YIGSKRGDS, YIGSKRGDV and YIGSKRGDF were observed. By comparing their activities it was found that by coupling YIGSK and RGD containing peptides the antiplatelet aggregation effects of some of the compounds may be enhanced.

Key words: YIGSK, RGD containing peptides, Antiplatelet aggregation effects

Supporting: ^*This project was supported by the Natural Science Foundation of China.

迪丽努尔·莎比托夫, 赵明, 王超, 彭师奇^*. YIGSK和含RGD多肽的抗血小板聚集作用[J]. .

Dilinur Shabitofu, Ming Zhao, Chao Wang, Shi-Qi Peng^*. Antiplatelet Aggregation Effects of YIGSK and RGD Containing Peptides[J]. .