地血香乙醇提取物对小鼠肝细胞中抗氧化酶活性的影响

地血香乙醇提取物对小鼠肝细胞中抗氧化酶活性的影响

杨秀伟, 陈道峰, 徐国钧, 服部征雄, 难波恒雄

1. 北京医科大学药学院, 北京 100083
2. 上海医科大学药学院, 上海 200032;
3. 中国南京药科大学, 南京 210009; 4
4. 日本富山医科药科大学和汉药研究所, 富山 930-01

收稿日期:1993-04-20 修回日期:1993-10-28 出版日期:1994-12-15 发布日期:1994-12-15

Effects of Ethanolic Extract of the Stems of Kadsura heteroclita on Anhioxidative Enzymes Activity in Liver Cytosol of mice in vivo

Xiu-Wei Yang, Dao-Feng Chen, Guo-Jun Xu, Masao Hattori, Tsuneo Namba

1. School of Pharmaceutical Sciences Beijing Medical University, Beijing100083;
2. School of Pharmaceutical Sciences, Shanghai Medical University, Shanghai 200032;
3. China Pharmaceutical University, Nanjing 210009;
4. Research Institute for Wakan-Yaku, Toyama Medical and Pharmaceutical University Toyama 930-01, Japan

Received:1993-04-20 Revised:1993-10-28 Online:1994-12-15 Published:1994-12-15

摘要/Abstract

摘要： 本文报道地血香乙醇提取物和其主要成分Kadsurin对小鼠肝细胞中抗氧化酶活性的影响。地血香和Kdsurin能够明显增加肝细胞中超氧物歧化酶和过氧化氢酶的活性, 而对谷胱甘肽过氧化物酶活性的影响无统计学意义。

关键词: 抗脂质过氧化作用, 超氧物歧化酶, 过氧化氢酶, 谷胱甘肽过氧化物酶, 地血香

Abstract: The effect of ethanolic extract of the stems of Kadeura heteroclita ( KHE) and its main constituent kadsurin, on the activities of anti-oxidative enzymes in liver cytosol of mice in vivo were studied. It is suggested that KHE and kadsurin increased the activities of superoxide dismutase (SOD) and catalase in liver cytosol of mice, but showed no statistical significance in altering the activity of GSH-peroxidase.

Key words: Anti-lipid peroxidation, Speroxide dismutase (SOD), Catalase, GSH peroxidase, Kadsura heteroclita

Supporting:

杨秀伟, 陈道峰, 徐国钧, 服部征雄, 难波恒雄. 地血香乙醇提取物对小鼠肝细胞中抗氧化酶活性的影响[J]. .

Xiu-Wei Yang, Dao-Feng Chen, Guo-Jun Xu, Masao Hattori, Tsuneo Namba. Effects of Ethanolic Extract of the Stems of Kadsura heteroclita on Anhioxidative Enzymes Activity in Liver Cytosol of mice in vivo[J]. .

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