大麻中活性成分的气相色谱分析法及国内主要产区大麻活性成分含量的普查

大麻中活性成分的气相色谱分析法及国内主要产区大麻活性成分含量的普查

朱霁虹, 李永庆, 鲍兴华

中国药品生物制品检定所国家麻醉品实验室, 北京 100050

收稿日期:1992-01-18 修回日期:1992-10-04 出版日期:1992-12-15 发布日期:1992-12-15

GC Determination of Active Cannabinoids in Cannabis of Chinese Origin and Survey of Their Contents

Ji-Hong Zhu, Yong-Qing Li, Xing-Hua Bao

National Laboratory of Narcotic Drugs; National Institute for the Control of Pharmaceutical and Biological Products; Beijing 100050

Received:1992-01-18 Revised:1992-10-04 Online:1992-12-15 Published:1992-12-15

摘要/Abstract

摘要： 采用有机溶剂提取大麻活性成分后, 再用气相色谱内标法检测大麻中大麻二酚CBD、∆⁹-四氢大麻酚∆⁹-THC和大麻酚CBN三种活性成分的方法, 方法简便, 结果准确。用于全国十个省市大麻样品的检测, 对其中大麻主要产区——新疆和云南大部分地区大麻活性成分含量进行了普查, 从而取得了我国大麻中活性成分含量情况的第一手资料。在检测方法建立过程中, 作者成功地从大麻植物中提取分离出CBD、∆⁹-THC和CBN对照品。解决了检测中面临的难题。

关键词: 大麻, 大麻二酚, 大麻酚, △9-四氢大麻酚, 气相色谱分析

Abstract: A method of GC determination using tetracosane as the internal standard for active cannabinoids cannabidiol. ∆⁹-tetrahydrocannabinol and cannabinol of cannabis is described. The method is simple and accurate and has been applied to investigate the contents of active cannabinoids in cannabis of Chinese origin. Information was obtained from provinces and autonomous region of China. Three pure cannabinoids used as the reference substances were extracted and isolated successfully from cannabis.

Key words: Cannabis sativa, Cannabidiol (CBD), Cannabinol (CBN), △9-Tetrahydro-cannabinol (△9-THC), Gas chromatography

Supporting:

朱霁虹, 李永庆, 鲍兴华. 大麻中活性成分的气相色谱分析法及国内主要产区大麻活性成分含量的普查[J]. .

Ji-Hong Zhu, Yong-Qing Li, Xing-Hua Bao. GC Determination of Active Cannabinoids in Cannabis of Chinese Origin and Survey of Their Contents[J]. .