用二维核磁共振法研究肿足蕨碱的结构

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用二维核磁共振法研究肿足蕨碱的结构

陈亚民, 卢英华, 陈雁君, 马存升, 于德泉

1. 山东济宁医学院济宁 272113;
2. 中国医学科学院药物研究所北京 100050

收稿日期:1992-03-14 修回日期:1992-08-28 出版日期:1992-12-15 发布日期:1992-12-15

Application of 2D-NMR Techniques in the Structure Determination of Hypodematine

Ya-Min Chen, Ying-Hua Lu, Yan-Jun Chen, Cun-Sheng Ma, De-Quan Yu

1. Jining Medical College, Jining, Shandong 272113:
2. Institute of Materia Medica; Chinese Academy of Medical Sciences, Beijing 100050

Received:1992-03-14 Revised:1992-08-28 Online:1992-12-15 Published:1992-12-15

摘要/Abstract

摘要： 从金星蕨科植物山东肿足蕨Hypodematium sinense Iwatsuki的全草分得一种新化合物, 通过¹H-¹H COSY谱, ¹H-¹³C COSY谱和远程¹H-¹³C COSY谱确定其结构是一种具有苯基取代苯并氮杂环辛四烯新型骨架的生物碱, 命名为肿足蕨碱HypodematineI。

关键词: 山东肿足蕨, 肿足蕨碱, 二维核磁共振

Abstract: A novel alkaloid, named hypodematine, was isolated from the whole plant of a fern.Htpodematium sinemse lwatsuki.Its structure has been elucidated to have a novel skeleton of benzo-azacyclooctatetraene with a phenyl substituent by means of ¹H-¹H COSY. ¹H-¹³C COSY.and long-range ¹H-¹³C COSY spectroscopy.

Key words: Hypodematium sinense, Hypodematine, 2D-NMR

Supporting:

陈亚民, 卢英华, 陈雁君, 马存升, 于德泉. 用二维核磁共振法研究肿足蕨碱的结构[J]. .

Ya-Min Chen, Ying-Hua Lu, Yan-Jun Chen, Cun-Sheng Ma, De-Quan Yu. Application of 2D-NMR Techniques in the Structure Determination of Hypodematine[J]. .

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