http://jcps.bjmu.edu.cn

中国药学(英文版) ›› 2024, Vol. 33 ›› Issue (7): 587-596.DOI: 10.5246/jcps.2024.07.043

• 【综述】 •    下一篇

骨质疏松症中联合和序贯治疗的进展

郑佳1, 付颖2,3,*()   

  1. 1. 首都医科大学附属北京潞河医院, 北京 101149
    2. 首都医科大学附属北京潞河医院 内分泌代谢与免疫性疾病中心, 北京 101149
    3. 糖尿病防治研究北京市重点实验室, 北京 101149
  • 收稿日期:2023-11-23 修回日期:2023-12-14 接受日期:2024-01-08 出版日期:2024-07-30 发布日期:2024-07-30
  • 通讯作者: 付颖

Advancements in sequential and combination treatments for osteoporosis

Jia Zheng1, Ying Fu2,3,*()   

  1. 1 Beijing Luhe Hospital, Capital Medical University, Beijing 101149, China
    2 Center for Endocrine Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing 101149, China
    3 Beijing Key Laboratory of Diabetes Research and Care, Beijing 101149, China
  • Received:2023-11-23 Revised:2023-12-14 Accepted:2024-01-08 Online:2024-07-30 Published:2024-07-30
  • Contact: Ying Fu
  • Supported by:
    The Undergraduate Research Innovation Program of Capital Medical University (Grant No. XSKY2021387).

摘要:

骨质疏松症是一种常见的系统性退行性疾病, 对中国的国民健康构成了重大挑战, 尤其会引起骨折等并发症。骨质疏松症的治疗干预主要包括骨吸收抑制剂和骨形成促进剂。许多研究强调了使用不同药物类型的序贯和联合治疗的重要性。这些方法在增加骨密度、降低骨折风险和预防骨质疏松症进展方面显示出显著的疗效。本文旨在整合各种序贯治疗方案, 为临床医生在实践中提供有价值的见解。

关键词: 骨质疏松症, 序贯治疗, 联合治疗

Abstract:

Osteoporosis, a prevalent systemic degenerative disease, poses significant challenges to China’s national health, particularly due to complications such as fractures. Therapeutic interventions for osteoporosis primarily involve bone resorption inhibitors (antiresorptive) and bone formation promoters (anabolic). Numerous studies underscore the importance of sequential and combination treatments using diverse drug types. Such approaches have shown considerable efficacy in increasing bone mineral density, reducing fracture risk, and preventing the progression of osteoporosis. This article aimed to consolidate various sequential treatment schemes, offering valuable insights for clinicians in their practice.

Key words: Osteoporosis, Sequential treatment, Combination treatment

Supporting: