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Antioxidant Constituents from G. inflata Bat Root

Kun Zou, Yu-Ying Zhao, Nai-Wu Fu, Liang Qiao, Ru-Yi Zhang   

  1. 1. School of Pharmaceutical Sciences; Beijing Medical University; Beijing 100083;
    2. Institution of Oncologr The Chinese Academy of Medical Sclences; Beijing100021
  • Received:1996-04-14 Revised:1996-07-01 Online:1996-12-15 Published:1996-12-15

Abstract: Continuing the previous report (1), seventeen compounds were isolated from the roots and rhizoma of Glycyrrhiza inflata Bat. On the basis of spectroscopic methods five of them were identified as sucrose (1), 4’,5,7-trihydroxy-8-prenyl-flavonc (2), liquiritigenin (3), formononetin (4), and glabrone (5) (1), (4) and (5) were obtained from this plant for the first time. Their antioxidant activities were observed in three oxidizing systems in vitro. (2), (3) and (5) showed remarkable activities in scavenging O2.- (5) exhibited good activity in inhibiting hemolysis induced by H2O2 (3) and (5) displayed higher inhibitory action on (HpD+hv)-induced hemolysis than som typical antioxidants.

Key words: Glycyrrhiza inflata, Flavonoids, Glabrone, Antioxidant

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