Chemical constituents from the roots of Polygala sibirica L.

Abstract

Abstract:

To investigate the chemical constituents of the roots of Polygala sibirica L. The separation and purification were performed by solvent extraction and repeated chromatography with silica gel, Sephadex LH-20, ODS columns, and semiprep. HPLC. The structures were elucidated by spectral analysis. Twelve known compounds were isolated and identified as tenuifoliside A (1), tenuifoliside B (2), glomeratose A (3), 3',6-disinapoyl sucrose (4), sibiricose A5 (5), sibiricose A6 (6), sibiricose A1 (7), sibiricose A2 (8), polygalatenoside E (9), 1-O-L-arabinopyranosyl-O-(6→1)-β-D-glucopyranosyl-salicylate (10), canthoside A (11), and methyl- 3,4,5-trimethoxycinnamate (12). Compound 11 was obtained from genus Polygala for the first time, and compounds 2, 9, 10 and 12 were isolated from this plant for the first time.

Key words: Polygalaceae, Polygalaceae, Polygala sibirica L., Polygala sibirica L., Chemical constituents, Chemical constituents, ,

CLC Number:

R284.2

Supporting:

Yu-Hong Zhou, Yong Jiang, Jing Wen, Yu-Ping Chen, Peng-Fei Tu*. Chemical constituents from the roots of Polygala sibirica L.[J]. .

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Chemical constituents from the roots of Polygala sibirica L.

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